Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
Abstract This 2022 European Atherosclerosis Society lipoprotein (a)[Lp (a)] consensus
statement updates evidence for the role of Lp (a) in atherosclerotic cardiovascular disease …

Lipoprotein (a) and cardiovascular and valvular diseases: a genetic epidemiological perspective

BJ Arsenault, PR Kamstrup - Atherosclerosis, 2022 - Elsevier
Rates of atherosclerotic cardiovascular diseases (CVD) in the Western world have
spectacularly decreased over the past 50 years. However, a substantial proportion of high …

[HTML][HTML] Lipoprotein (a) measurement issues: are we making a mountain out of a molehill?

F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] became besides LDL cholesterol one of the most attractive
targets for intervention in cardiovascular disease. Strong genetic evidence supports the …

Clinical Trial Design for Lipoprotein(a)-Lowering Therapies: JACC Focus Seminar 2/3

WA Malick, SN Goonewardena, W Koenig… - Journal of the American …, 2023 - jacc.org
Abstract Lipoprotein (a)[Lp (a)] is a source of residual risk in patients with atherosclerotic
cardiovascular disease (ASCVD). Clinical trials of fully human monoclonal antibodies …

[HTML][HTML] Frequent questions and responses on the 2022 lipoprotein (a) consensus statement of the European Atherosclerosis Society

F Kronenberg, S Mora, ESG Stroes, BA Ference… - Atherosclerosis, 2023 - Elsevier
Abstract In 2022, the European Atherosclerosis Society (EAS) published a new consensus
statement on lipoprotein (a)[Lp (a)], summarizing current knowledge about its causal …

Lipoprotein (a) and carotid intima-media thickness in children with familial hypercholesterolaemia in the Netherlands: a 20-year follow-up study

LM de Boer, A Wiegman, J Kroon… - The lancet Diabetes & …, 2023 - thelancet.com
Background Elevated lipoprotein (a) and familial hypercholesterolaemia are both
independent risk conditions for cardiovascular disease. Although signs of atherosclerosis …

Lipoprotein (a) and ethnicities

A Mehta, V Jain, A Saeed, JJ Saseen, M Gulati… - Atherosclerosis, 2022 - Elsevier
The initial studies focusing on lipoprotein (a)[Lp (a)] and its role in atherosclerotic
cardiovascular disease were conducted exclusively in Whites. Subsequently, multiple large …

Consensus and guidelines on lipoprotein (a)–seeing the forest through the trees

F Kronenberg, S Mora, ESG Stroes - Current opinion in lipidology, 2022 - journals.lww.com
Since the contribution of high Lp (a) concentrations to global ASCVD risk has been
underestimated in the past, a clear recommendation to measure Lp (a) at least once in a …

Lipoprotein (a) and diabetes mellitus

C Lamina, NC Ward - Atherosclerosis, 2022 - Elsevier
Lp (a) and diabetes are both known and established risk factors for the development of
cardiovascular disease. However, studies trying to link both risk factors find an inverse …

[HTML][HTML] Daring to dream: Targeting lipoprotein (a) as a causal and risk-enhancing factor

ML Koschinsky, ESG Stroes, F Kronenberg - Pharmacological Research, 2023 - Elsevier
Abstract Lipoprotein (a)[Lp (a)], a distinct lipoprotein class, has become a major focus for
cardiovascular research. This review is written in light of the recent guideline and consensus …