[HTML][HTML] Self-eating for muscle fitness: autophagy in the control of energy metabolism
D Sebastian, A Zorzano - Developmental Cell, 2020 - cell.com
Cellular processes that sense and transmit metabolic changes are crucial for adaptation to
external signals. In this regard, autophagy provides energy upon nutrient deprivation and …
external signals. In this regard, autophagy provides energy upon nutrient deprivation and …
[HTML][HTML] Effect of aerobic exercise training and deconditioning on oxidative capacity and muscle mitochondrial enzyme machinery in young and elderly individuals
AM Fritzen, SP Andersen, KAN Qadri… - Journal of Clinical …, 2020 - mdpi.com
Mitochondrial dysfunction is thought to be involved in age-related loss of muscle mass and
function (sarcopenia). Since the degree of physical activity is vital for skeletal muscle …
function (sarcopenia). Since the degree of physical activity is vital for skeletal muscle …
Autophagy-dependent beneficial effects of exercise
JF Halling, H Pilegaard - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Exercise has long been recognized as a powerful physiological stimulus for a wide variety of
metabolic adaptations with implications for health and performance. The metabolic effects of …
metabolic adaptations with implications for health and performance. The metabolic effects of …
Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess
AM Lundsgaard, KA Sjøberg, LD Høeg, J Jeppesen… - Diabetes, 2017 - Am Diabetes Assoc
To understand the mechanisms in lipid-induced insulin resistance, a more physiological
approach is to enhance fatty acid (FA) availability through the diet. Nine healthy men …
approach is to enhance fatty acid (FA) availability through the diet. Nine healthy men …
[HTML][HTML] Involvement of sirtuins and klotho in cardioprotective effects of exercise training against waterpipe tobacco smoking-induced heart dysfunction
Despite its negative effect on the cardiovascular system, waterpipe smoking (WPS) is
currently popular worldwide, especially among youth. This study investigated the effects of …
currently popular worldwide, especially among youth. This study investigated the effects of …
Autophagy is induced by resistance exercise in young men, but unfolded protein response is induced regardless of age
Aim Autophagy and unfolded protein response (UPR) appear to be important for skeletal
muscle homoeostasis and may be altered by exercise. Our aim was to investigate the effects …
muscle homoeostasis and may be altered by exercise. Our aim was to investigate the effects …
Physical exercise attenuates age‐related muscle atrophy and exhibits anti‐ageing effects via the adiponectin receptor 1 signalling
YL Chen, YC Ma, J Tang, D Zhang… - Journal of cachexia …, 2023 - Wiley Online Library
Background Although the adiponectin signalling exerts exercise‐mimicking effects, whether
this pathway contributes to the anti‐ageing benefits of physical exercise has not been …
this pathway contributes to the anti‐ageing benefits of physical exercise has not been …
Dietary fuels in athletic performance
AM Fritzen, AM Lundsgaard, B Kiens - Annual review of nutrition, 2019 - annualreviews.org
Focusing on daily nutrition is important for athletes to perform and adapt optimally to
exercise training. The major roles of an athlete's daily diet are to supply the substrates …
exercise training. The major roles of an athlete's daily diet are to supply the substrates …
[HTML][HTML] Salubrinal promotes phospho-eIF2α-dependent activation of UPR leading to autophagy-mediated attenuation of iron-induced insulin resistance
Identification of new mechanisms mediating insulin sensitivity is important to allow validation
of corresponding therapeutic targets. In this study, we first used a cellular model of skeletal …
of corresponding therapeutic targets. In this study, we first used a cellular model of skeletal …
[HTML][HTML] ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2
AM Fritzen, J Domingo-Espín, AM Lundsgaard… - Molecular …, 2020 - Elsevier
Objective Acute administration of the main protein component of high-density lipoprotein,
apolipoprotein AI (ApoA-1), improves glucose uptake in skeletal muscle. The molecular …
apolipoprotein AI (ApoA-1), improves glucose uptake in skeletal muscle. The molecular …