The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …
Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?
M Ge, Y Zhu, M Wei, H Piao, M He - … et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
The therapies targeting mutations of driver genes in cancer have advanced into clinical trials
for a variety of tumors. In glioblastoma (GBM), epidermal growth factor receptor (EGFR) is …
for a variety of tumors. In glioblastoma (GBM), epidermal growth factor receptor (EGFR) is …
Exosomes; multifaceted nanoplatform for targeting brain cancers
At the moment, anaplastic changes within the brain are challenging due to the complexity of
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …
Study on the Role of an Erythrocyte Membrane‐Coated Nanotheranostic System in Targeted Immune Regulation of Alzheimer's Disease
Y Su, Y Huang, Q Kou, L Lu, H Jiang, X Li… - Advanced …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases in the
elderly population. Despite significant advances in studies of the pathobiology on AD, there …
elderly population. Despite significant advances in studies of the pathobiology on AD, there …
Intranasal Drug Delivery by Nanotechnology: Advances in and Challenges for Alzheimer's Disease Management
Alzheimer's disease, a progressive neurodegenerative condition, is characterized by a
gradual decline in cognitive functions. Current treatment approaches primarily involve the …
gradual decline in cognitive functions. Current treatment approaches primarily involve the …
The Promise of Molecular Imaging: Focus on Central Nervous System Infections
Central nervous system (CNS) infections can lead to high mortality and severe morbidity.
Diagnosis, monitoring, and assessing response to therapy of CNS infections is particularly …
Diagnosis, monitoring, and assessing response to therapy of CNS infections is particularly …
Next-generation viral nanoparticles for targeted delivery of therapeutics: Fundamentals, methods, biomedical applications, and challenges
JS Tan, MNB Jaffar Ali, BK Gan… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Viral nanoparticles (VNPs) are virus-based nanocarriers that have
been studied extensively and intensively for biomedical applications. However, their clinical …
been studied extensively and intensively for biomedical applications. However, their clinical …
[HTML][HTML] Development of computational intelligence models for assessment of drug nanonization using green chemistry technique: Improvement of drug solubility
B Huwaimel, TN Alharby - Case Studies in Thermal Engineering, 2023 - Elsevier
Determination of solubility via theoretical approaches was carried out in this study. Because
of its importance to the expansion of the pharmaceutical industry, this study models …
of its importance to the expansion of the pharmaceutical industry, this study models …
The inverse electron demand Diels–Alder cycloaddition with carbon‐11 and fluorine‐18: A gateway to pretargeted imaging across the blood–brain barrier
SH Zientek, S Thompson, SM Sephton… - Journal of Labelled …, 2023 - Wiley Online Library
There is increased focus on developing tools to image large biomolecules, such as
antibodies, within the brain using positron emission tomography (PET). The inverse electron …
antibodies, within the brain using positron emission tomography (PET). The inverse electron …
A Scoping Review of Focused Ultrasound Enhanced Drug Delivery for Across the Blood–Brain Barrier for Brain Tumors
CM Young, A Viña-González… - Operative …, 2022 - journals.lww.com
METHODS: A review of current literature was conducted through a MEDLINE search
inclusive of articles on FUS, BBB, and brain tumor barrier, including human, modeling, and …
inclusive of articles on FUS, BBB, and brain tumor barrier, including human, modeling, and …