Nebivolol: the somewhat-different β-adrenergic receptor blocker

T Münzel, T Gori - Journal of the American College of Cardiology, 2009 - jacc.org
Although its clinical use in Europe dates almost 10 years, nebivolol is a β-blocker that has
been only recently introduced in the US market. Like carvedilol, nebivolol belongs to the …

Beta-blockers in hypertension

CVS Ram - The American journal of cardiology, 2010 - Elsevier
Beta blockers have been used in the treatment of cardiovascular conditions for decades.
Despite a long history and status as a guideline-recommended treatment option for …

Nebivolol: impact on cardiac and endothelial function and clinical utility

JE Toblli, F DiGennaro, JF Giani… - Vascular Health and …, 2012 - Taylor & Francis
Endothelial dysfunction is a systemic pathological state of the endothelium characterized by
a reduction in the bioavailability of vasodilators, essentially nitric oxide, leading to impaired …

Protective effects of nebivolol from oxidative stress to prevent hypertension-related target organ damage

A Coats, S Jain - Journal of human hypertension, 2017 - nature.com
Hypertension is one of the leading risk factors for morbidity and mortality in patients with
cardiovascular and cerebrovascular diseases and renal impairment. It also leads to target …

Nebivolol: Haemodynamic effects and clinical significance of combined β-blockade and nitric oxide release

O Kamp, M Metra, S Bugatti, L Bettari, A Dei Cas… - Drugs, 2010 - Springer
Nebivolol is a third-generation β-adrenergic receptor antagonist (β-blocker) with high
selectivity for β 1-adrenergic receptors. In addition, it causes vasodilatation via interaction …

A Randomized, Double‐Blind, Placebo‐Controlled Parallel‐Group Study to Assess the Efficacy and Safety of Nebivolol, a Novel β‐Blocker, in Patients With Mild to …

RJ Weiss, MA Weber, AA Carr… - The Journal of Clinical …, 2007 - Wiley Online Library
This double‐blind, multicenter, randomized placebo‐controlled study evaluated the
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …

Изучение цитокиновой активности у больных острым инфарктом миокарда

ИИ Чукаева, НВ Орлова, ЯГ Спирякина… - Российский …, 2010 - cyberleninka.ru
Острый инфаркт миокарда является тяжелым сердечно-сосудистым заболеванием. В
ряде исследований выявлена зависимость течения инфаркта миокарда не только от …

A review of the safety and efficacy of nebivolol in the mildly hypertensive patient

C John - Vascular health and risk management, 2007 - Taylor & Francis
Nebivolol is a third generation beta-blocker, which can be distinguished from other beta-
blockers by its hemodynamic profile. It combines beta-adrenergic blocking activity with a …

Chronic Nebivolol Treatment Suppresses Endothelin-1–Mediated Vasoconstrictor Tone in Adults With Elevated Blood Pressure

KJ Diehl, BL Stauffer, CA Dow, TD Bammert… - …, 2016 - Am Heart Assoc
Endothelin-1 (ET-1) plays a major role in the pathophysiology of hypertension and its
associated cardiovascular risk. We tested the hypothesis that chronic nebivolol treatment …

Optimal use of β-blockers in high-risk hypertension: a guide to dosing equivalence

JB McGill - Vascular health and risk management, 2010 - Taylor & Francis
Hypertension is the number one diagnosis made by primary care physicians, placing them
in a unique position to prescribe the antihypertensive agent best suited to the individual …