Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS)

Q Huang, Y Le, S Li, Y Bian - Respiratory Research, 2024 - Springer
Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …

[HTML][HTML] The role of long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) in immune diseases

D Jing, F Zhu, Z Xu, G Zhang, G Zhou - Transplant Immunology, 2022 - Elsevier
The long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) has
been shown to be involved in the pathogenesis of several diseases. Herein, we discuss …

Identification of potential biomarkers and pathways for sepsis using RNA sequencing technology and bioinformatic analysis

R Yu, Y Wang, Q Liang, Y Xu, AE Yusf, L Sun - Heliyon, 2023 - cell.com
Long non-coding RNAs (lncRNAs) has been proven by many to play a crucial part in the
process of sepsis. To obtain a better understanding of sepsis, the molecular biomarkers …

Epigallocatechin-3-gallate ameliorates inflammatory injury caused by sepsis by regulating the lncRNA PVT1/miR-16-5p/TLR4 axis

W Yuan, S Li, YN Yang, H Gao, C Liu - Cytokine, 2023 - Elsevier
Background Sepsis is identified as a severe inflammatory disease. Epigallocatechin-3-
gallate (EGCG) has been reported to be a powerful anti-inflammatory chemical substance in …

[HTML][HTML] Exploring the translational landscape of the long noncoding RNA transcriptome in acute respiratory distress syndrome: it is a long way to the top

T Belmonte, C Rodríguez-Muñoz… - European …, 2024 - err.ersjournals.com
Acute respiratory distress syndrome (ARDS) poses a significant and widespread public
health challenge. Extensive research conducted in recent decades has considerably …

Neutrophil–macrophage communication via extracellular vesicle transfer promotes itaconate accumulation and ameliorates cytokine storm syndrome

H Kang, T Liu, Y Wang, W Bai, Y Luo… - Cellular & Molecular …, 2024 - nature.com
Cytokine storm syndrome (CSS) is a life-threatening systemic inflammatory syndrome
involving innate immune hyperactivity triggered by various therapies, infections, and …

Polydatin alleviates sepsis‑induced acute lung injury via downregulation of Spi‑B

Q Liao, F Li, M Xue, W Chen, Z Tao… - Biomedical …, 2023 - spandidos-publications.com
Sepsis‑induced acute lung injury (ALI) is related to the dysregulation of inflammatory
responses. Polydatin supplement was reported to exhibit anti‑inflammatory effects in several …

[HTML][HTML] miR-142-5p encapsulated by serum-derived extracellular vesicles protects against acute lung injury in septic rats following remote ischemic preconditioning …

W Zhu, X Huang, S Qiu, L Feng, Y Wu… - Journal of Innate …, 2022 - karger.com
This study intends to investigate the effects of miR-142-5p encapsulated by serum-derived
extracellular vesicles (EVs) on septic acute lung injury (ALI) following remote ischemic …

Role of ATF3 triggering M2 macrophage polarization to protect against the inflammatory injury of sepsis through ILF3/NEAT1 axis

W Wang, R Xu, P He, Y Xiong, H Zhao, X Fu, J Lin… - Molecular …, 2024 - Springer
Background Sepsis is a systemic inflammatory response which is frequently associated with
acute lung injury (ALI). Activating transcription factor 3 (ATF3) promotes M2 polarization …

[HTML][HTML] Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression

O Sweef, R Mahfouz, T Taşcıoğlu… - International Journal of …, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer represent formidable
challenges in global health, characterized by intricate pathophysiological mechanisms and …