Genus Helleborus: a comprehensive review of phytochemistry, pharmacology and clinical applications

S Li, X Chen, J Tang, D Zhang, Y Jiang… - Natural Product …, 2024 - Taylor & Francis
The genus Helleborus belongs to the Ranunculaceae family, distributed in southeastern
Europe and western Asia. In folk medicine, it is commonly used as an anti-inflammatory and …

Bufadienolides and ecdysteroids from the whole plants of Helleborus niger and their cytotoxicity

A Yokosuka, M Inomata, Y Yoshizawa, T Iguchi… - Journal of natural …, 2021 - Springer
Abstract A new bufadienolide (1), two new bufadienolide glycosides (2 and 3), a new
ecdysteroid (4), and four known compounds (5–8), were isolated from the whole plants of …

Steroidal constituents in the whole plants of Helleborus niger and their cytotoxic activity in vitro

Y Yoshizawa, A Yokosuka, M Inomata, T Iguchi… - Phytochemistry, 2024 - Elsevier
Phytochemical investigation of the whole plants of Helleborus niger L.(Ranunculaceae)
resulted in the isolation of five undescribed compounds, including one bufadienolide (1), two …

Steroidal Glycosides from the Aerial Parts of Avena sativa L. and Their Cytotoxic Activity

A Yokosuka, K Ishihara, T Yamada… - Journal of Agricultural …, 2021 - ACS Publications
Twelve steroidal glycosides (1–12) were isolated from the aerial parts of Avena sativa
L.(Poaceae). Among the isolated compounds, 1 was directly isolated from the plant for the …

Steroidal saponins from the roots of Paris verticillata and their anti-proliferative and anti-inflammatory activities

Y Liu, Y Bi, JT Bai, SY Wang, JT Wu, YK Jiang, P Jiang… - Phytochemistry, 2024 - Elsevier
Thirteen previously undescribed steroidal saponins, named parisverticilloside AM (1–13)
and twenty known steroidal saponins (14–33) were isolated from ethanol extract of the roots …

Structure Elucidation of 16 Undescribed Steroidal Glycosides from the Underground Parts of Agapanthus africanus and Apoptosis-Inducing Activity in Small-Cell …

N Takahashi, T Iguchi, A Nagamine, R Shirai… - ACS …, 2023 - ACS Publications
To explore new candidates for anticancer agents from natural products, the underground
parts of Agapanthus africanus, commonly used as an ornamental plant, were investigated …

A previously undescribed phenolic compound from Acanthus ilicifolius L.

NT Mai, LT Huyen, LTM Hanh… - Vietnam Journal of …, 2023 - Wiley Online Library
The plants Acanthus ilicifolius L.(Acanthaceae) are used in Vietnamese folk medicine for the
treatment of stomach pain, hepatitis, asthama, and rheumatism. Phytochemical study on the …

Suaedamas A–D: Four New Compounds from the Aerial Parts of Suaeda maritima with Inhibition of NO Production Activity

B Thi Nha Trang, B Thi Mai Anh, N Thi Mai… - Chemistry & … - Wiley Online Library
Four new compounds, suaedamas A–D (1–4), and seven known ones (5–11) were isolated
from the aerial parts of Suaeda maritima. Their chemical structures were evaluated by the IR …