Primary sclerosing cholangitis (PSC) was declared one of the biggest unmet needs in
hepatology during ILC 2016 in Berlin. Since then, not much has changed unfortunately …

The process of drug development is expensive and time-consuming. In contrast, drug
repurposing can be introduced to clinical practice more quickly and at a reduced cost. Over …

Autoimmune liver diseases (AILDs) include primary biliary cholangitis (PBC), primary
sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH), a family of chronic immune …

Background Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease, with
unclear pathogenesis. Although immune disorders, especially T cell infiltration, are thought …

Background Primary sclerosing cholangitis (PSC) is a kind of cholestatic liver disease
without effective therapies and its pathogenesis is largely unknown. Methods We performed …

Background and aims The comorbidity between bipolar disorder (BD) and inflammatory
bowel disease (IBD) has been widely reported in observational studies. However, unclear …

Abstract Background and Aim The causal linkage between primary sclerosing cholangitis
(PSC) and kidney function is unexplored despite their potential for long‐term detrimental …

Aim Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by
inflammation of the intra‐and extrahepatic bile ducts. Pathogenesis of PSC is still enigmatic …

Letter: Mendelian randomization ‐ new perspective in inflammatory bowel disease and pancreatic
cancer? Authors' reply Page 1 Aliment Pharmacol Ther. 2023;58:145–146 …

Heart failure (HF) is a common cardiovascular disease that poses significant morbidity and
mortality risks. While genome-wide association studies reporting on HF abound, its genetic …