The study of plant mitochondria started in earnest around 1950 with the first isolations of
mitochondria from animal and plant tissues. The first 35 years were spent establishing the …

Complex I is one of the major respiratory complexes, conserved from bacteria to mammals. It
oxidises NADH, reduces quinone and pumps protons across the membrane, thus playing a …

Protein complexes of the mitochondrial respiratory chain assemble into respiratory
supercomplexes. Here we present the high-resolution electron cryo-microscopy structure of …

Respiration is a core biological energy–converting process whose last steps are carried out
by a chain of multisubunit complexes in the inner mitochondrial membrane. To probe the …

The last steps of cellular respiration—an essential metabolic process in plants—are carried
out by mitochondrial oxidative phosphorylation. This process involves a chain of multi …

Complex I (CI) is the largest protein complex in the mitochondrial oxidative phosphorylation
electron transport chain of the inner mitochondrial membrane and plays a key role in the …

Mitochondrial complex III (CIII2) and complex IV (CIV), which can associate into a higher-
order supercomplex (SC III2+ IV), play key roles in respiration. However, structures of these …

Tetrahymena thermophila, a classic ciliate model organism, has been shown to possess
tubular mitochondrial cristae and highly divergent electron transport chain involving four …

Mitochondrial complex I is the main site for electron transfer to the respiratory chain and
generates much of the proton gradient across the inner mitochondrial membrane. Complex I …

Genetic variation is the major mechanism behind adaptation and evolutionary change. As
most proteins operate through interactions with other proteins, changes in protein complex …