Simple Summary The TCR is the T cell antigen receptor, and it is responsible of the T cell
activation, through the HLA-antigen complex recognition. Studying the TCR repertoire in …

An improved understanding of human T cell-mediated immunity in COVID-19 is important for
optimizing therapeutic and vaccine strategies. Experience with influenza shows that …

To better understand primary and recall T cell responses during coronavirus disease 2019
(COVID-19), it is important to examine unmanipulated severe acute respiratory syndrome …

Memory T cells are conventionally subdivided into T central memory (TCM) and T effector
memory (TEM) cells. However, a new subset of memory T cells named T memory stem cell …

Human CD1a is a non-polymorphic glycoprotein that presents lipid antigens to T cells. The
most obvious role of CD1a is associated with its expression on Langerhans cells in …

The human leukocyte antigen (HLA) system is a major factor controlling cancer
immunosurveillance and response to immunotherapy, yet its status in pediatric cancers …

Among the many oncology therapies, few have generated as much excitement as CAR-T.
The success of CAR therapy would not have been possible without the many discoveries …

Visceral leishmaniasis (VL) is a vector-borne neglected tropical protozoan disease with high
fatality and no certified vaccine. Conventional vaccine preparation is challenging and …

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis (EBL), which
has been reported worldwide. The expression of viral structural proteins: surface …

Despite annual vaccination, influenza B viruses (IBV) cause significant disease with
substantial health and socio-economic impacts. Novel vaccination strategies inducing …