Polymeric micelles and cancer therapy: An ingenious multimodal tumor-targeted drug delivery system

SK Hari, A Gauba, N Shrivastava, RM Tripathi… - Drug Delivery and …, 2023 - Springer
Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …

Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?

F Li, I Aljahdali, X Ling - Journal of Experimental & Clinical Cancer …, 2019 - Springer
Survivin (also named BIRC5) is a well-known cancer therapeutic target. Since its discovery
more than two decades ago, the use of survivin as a target for cancer therapeutics has …

Nanomedicine of synergistic drug combinations for cancer therapy–Strategies and perspectives

RX Zhang, HL Wong, HY Xue, JY Eoh… - Journal of Controlled …, 2016 - Elsevier
Nanomedicine of synergistic drug combinations has shown increasing significance in
cancer therapy due to its promise in providing superior therapeutic benefits to the current …

Multifunctional polymeric micelles for delivery of drugs and siRNA

AM Jhaveri, VP Torchilin - Frontiers in pharmacology, 2014 - frontiersin.org
Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-
shell structure have been used as versatile carriers for delivery of drugs as well as nucleic …

Nanotechnological carriers for cancer chemotherapy: the state of the art

M Estanqueiro, MH Amaral, J Conceição… - Colloids and surfaces B …, 2015 - Elsevier
Cancer is a term used for a heterogeneous group of malignant diseases in which abnormal
cells divide without control and are able to invade other tissues, resulting in metastasis …

Stimuli-sensitive nanopreparations for combination cancer therapy

A Jhaveri, P Deshpande, V Torchilin - Journal of controlled release, 2014 - Elsevier
Nanocarriers have revolutionized drug delivery practices over the past couple of decades,
primarily due to the advances in materials chemistry, nanotechnology and nanomedicine …

Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

L Zhu, F Perche, T Wang, VP Torchilin - Biomaterials, 2014 - Elsevier
Co-delivery of hydrophilic siRNA and hydrophobic drugs is one of the major challenges for
nanomaterial-based medicine. Here, we present a simple but multifunctional micellar …

Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy

MW Amjad, P Kesharwani, MCIM Amin… - Progress in polymer …, 2017 - Elsevier
Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat
diseases such as cancer. Nevertheless, substantial obstacles to its clinical applications have …

The Warburg effect and glucose-derived cancer theranostics

RK Tekade, X Sun - Drug Discovery Today, 2017 - Elsevier
Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Polymer vesicles: modular platforms for cancer theranostics

F Wang, J Xiao, S Chen, H Sun, B Yang… - Advanced …, 2018 - Wiley Online Library
As an emerging field that is receiving an increasing amount of interest, theranostics is
becoming increasingly important in the field of nanomedicine. Among the various smart …