Depressive disorders are among the leading causes of global disease burden, but there has
been limited progress in understanding the causes of and treatments for these disorders. In …

Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

The notion of climate anxiety has gained traction in the last years. Yet uncertainty remains
regarding the variations of climate anxiety across demographic characteristics (eg, gender …

Background Depressive disorders were a leading cause of burden in the Global Burden of
Disease (GBD) 1990 and 2000 studies. Here, we analyze the burden of depressive …

Objective: Diagnosis is a cornerstone of clinical practice for mental health care providers, yet
traditional diagnostic systems have well-known shortcomings, including inadequate …

Background Many clinical trials have assessed treatments for depressive disorders and
bipolar depression. However, whether, and which, assessed outcome domains really matter …

Previous studies have established that scores on Major Depressive Disorder scales are
correlated with measures of impairment of psychosocial functioning. It remains unclear …

Reflecting major contemporary developments in theory and clinical practice, the second
edition of this authoritative guide has been significantly rewritten with 85% new material …

Background Studies have identified high rates of mental disorders in refugees, but most
used self-report measures of psychiatric symptoms. In this study, we examined the …

Approximately one-third of individuals in a major depressive episode will not achieve
sustained remission despite multiple, well-delivered treatments. These patients experience …