Coxiella burnetii is the causative agent of Q fever, a disease with a spectrum of
presentations from the mild to fatal, including chronic sequelae. Since its discovery in 1935 …

Coxiella burnetii is the causative agent of the zoonotic disease Q fever. Since its first
recognition as a disease in the 1930s, the knowledge about the agent and the disease itself …

Coxiella burnetii is the bacterial causative agent of the zoonosis Q fever. The current human
Q fever vaccine, Q-VAX®, is a fixed, whole cell vaccine (WCV) licensed solely for use in …

T cell-mediated immunity plays a central role in the control and clearance of intracellular
Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel …

Lipid droplets (LDs) are cytosolic lipid storage organelles that are important for cellular lipid
metabolism, energy homeostasis, cell signaling, and inflammation. Several bacterial, viral …

Q-VAX®, a whole cell, formalin-inactivated vaccine, is the only vaccine licensed for human
use to protect against Coxiella burnetii, the cause of Q fever. Although this vaccine provides …

Q fever is caused by the obligate intracellular bacterium, Coxiella burnetii, a designated
potential agent of bioterrorism because of its route of transmission, resistance to …

Brucella is an intracellular pathogen that causes abortion in domestic animals and undulant
fever in humans. Due to the lack of a human vaccine against brucellosis, animal vaccines …

Vaccination is the most important approach to counteract infectious diseases. Thus, the
development of new and improved vaccines for existing, emerging, and re-emerging …

Coxiella burnetii is an obligate intracellular bacterium which, in humans, causes the disease
Q fever. Although Q fever is most often a mild, self-limiting respiratory disease, it can cause a …