[HTML][HTML] Natural products in Alzheimer's disease therapy: would old therapeutic approaches fix the broken promise of modern medicines?

S Habtemariam - Molecules, 2019 - mdpi.com
Despite extensive progress in understanding the pathology of Alzheimer's disease (AD) over
the last 50 years, clinical trials based on the amyloid–beta (Aβ) hypothesis have kept failing …

Dietary pattern, gut microbiota, and Alzheimer's disease

M Zhang, D Zhao, G Zhou, C Li - Journal of agricultural and food …, 2020 - ACS Publications
Alzheimer's disease is the most common neurodegenerative disease. Until now, there has
been no specific medicine that can cure Alzheimer's disease or effectively reverse the …

Nano-enabled personalized nutrition: Developing multicomponent-bioactive colloidal delivery systems

DJ McClements - Advances in colloid and interface science, 2020 - Elsevier
There is growing interest in the production of foods and beverages with nutrient and
nutraceutical profiles tailored to an individual's specific nutritional requirements. In principle …

[HTML][HTML] Action mechanisms of curcumin in Alzheimer's disease and its brain targeted delivery

D Ege - Materials, 2021 - mdpi.com
AD is a chronic neurodegenerative disease. Many different signaling pathways, such as
Wnt/β-catenin, Notch, ROS/JNK, and PI3K/Akt/mTOR are involved in Alzheimer's disease …

Progress and perspectives of brain-targeting lipid-based nanosystems via the nasal route in Alzheimer's disease

H Akel, R Ismail, I Csoka - European Journal of Pharmaceutics and …, 2020 - Elsevier
Since health care systems dedicate substantial resources to Alzheimer's disease (AD), it
poses an increasing challenge to scientists and health care providers worldwide, especially …

[HTML][HTML] Pharmacotherapy of Alzheimer's disease: Seeking clarity in a time of uncertainty

N Husna Ibrahim, MF Yahaya, W Mohamed… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is recognized as a major health hazard that mostly affects people
older than 60 years. AD is one of the biggest medical, economic, and social concerns to …

Mitochondrial Dysfunction and Alpha‐Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?

SM Dos Santos, CFR Romeiro… - Oxidative medicine …, 2019 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder characterised by impairments in
the cognitive domains associated with orientation, recording, and memory. This pathology …

[HTML][HTML] Functional foods: an approach to modulate molecular mechanisms of Alzheimer's disease

A Atlante, G Amadoro, A Bobba, V Latina - Cells, 2020 - mdpi.com
A new epoch is emerging with intense research on nutraceuticals, ie,“food or food product
that provides medical or health benefits including the prevention and treatment of diseases” …

[HTML][HTML] Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Insights into the potential role of mercury in Alzheimer's disease

G Bjørklund, AA Tinkov, M Dadar, MM Rahman… - Journal of Molecular …, 2019 - Springer
Mercury (Hg), which is a non-essential element, is considered a highly toxic pollutant for
biological systems even when present at trace levels. Elevated Hg exposure with the …