Unleashing the potential of cell membrane-based nanoparticles for COVID-19 treatment and vaccination
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a particular
coronavirus strain responsible for the coronavirus disease 2019 (COVID-19), accounting for …
coronavirus strain responsible for the coronavirus disease 2019 (COVID-19), accounting for …
Shaping neonatal immunization by tuning the delivery of synergistic adjuvants via nanocarriers
Adjuvanted nanocarrier-based vaccines hold substantial potential for applications in novel
early-life immunization strategies. Here, via mouse and human age-specific in vitro …
early-life immunization strategies. Here, via mouse and human age-specific in vitro …
Mosaic receptor binding domain nanoparticles: towards fourth-generation vaccination
VP Chavda, V Apostolopoulos - Nanomedicine, 2023 - Taylor & Francis
Throughout the time since its origin, the coronavirus has had a tendency to change
continuously, which leads to the emergence of new viral variants. Variants may have …
continuously, which leads to the emergence of new viral variants. Variants may have …
Challenges and future directions for next-generation biomedical polymersomes
J Shi, Q Sun, W Wang, C Li, H Yin, H Li, R Teng… - Science China …, 2024 - Springer
As a major transport system in cells, naturally occurring vesicles play an important role to
ensure that the right cargo is shipped to the right destination at the right time. Similarly …
ensure that the right cargo is shipped to the right destination at the right time. Similarly …
Nanovaccines for Advancing Long-Lasting Immunity against Infectious Diseases
X Gao, X Wang, S Li, M Saif Ur Rahman, S Xu, Y Liu - ACS nano, 2023 - ACS Publications
Infectious diseases, particularly life-threatening pathogens such as small pox and influenza,
have substantial implications on public health and global economies. Vaccination is a key …
have substantial implications on public health and global economies. Vaccination is a key …
Development of T cell antigen-based human coronavirus vaccines against nAb-escaping SARS-CoV-2 variants
H Zhou, P Leng, Y Wang, K Yang, C Li, DM Ojcius… - Science Bulletin, 2024 - Elsevier
Currently approved vaccines have been successful in preventing the severity of COVID-19
and hospitalization. These vaccines primarily induce humoral immune responses; however …
and hospitalization. These vaccines primarily induce humoral immune responses; however …
The pivotal roles of the host immune response in the fine-tuning the infection and the development of the vaccines for SARS-CoV-2
W Alturaiki, A Mubarak, A Al Jurayyan… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT SARS-CoV2 infection induces various degrees of infections ranging from
asymptomatic to severe cases and death. Virus/host interplay contributes substantially to …
asymptomatic to severe cases and death. Virus/host interplay contributes substantially to …
[HTML][HTML] Self-cleaning formulations of mixed metal oxide-silver micro-nano structures with spiky coronae as antimicrobial coatings for fabrics and surfaces
Antimicrobial coatings are essential for controlling the spread of pathogens and restricting
their interface with hosts. These may be applied to masks as additional security to wearers …
their interface with hosts. These may be applied to masks as additional security to wearers …
[HTML][HTML] Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines
Several effective SARS-CoV-2 vaccines have been developed using different technologies.
Although these vaccines target the isolates collected early in the pandemic, many have …
Although these vaccines target the isolates collected early in the pandemic, many have …
A cGAMP-containing hydrogel for prolonged SARS-CoV-2 RBD subunit vaccine exposure induces a broad and potent humoral response
The SARS-CoV-2 virus spike protein, specifically its receptor binding domain (RBD), has
emerged as a promising target for generation of neutralizing antibodies. Although the RBD …
emerged as a promising target for generation of neutralizing antibodies. Although the RBD …