[HTML][HTML] Exercise-related changes of networks in aging and mild cognitive impairment brain

P Huang, R Fang, BY Li, SD Chen - Frontiers in aging neuroscience, 2016 - frontiersin.org
Aging and mild cognitive impairment (MCI) are accompanied by decline of cognitive
functions. Meanwhile, the most common form of dementia is Alzheimer's disease (AD) …

[HTML][HTML] PET/MR imaging: new frontier in Alzheimer's disease and other dementias

XY Zhang, ZL Yang, GM Lu, GF Yang… - Frontiers in molecular …, 2017 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia; a progressive
neurodegenerative disease that currently lacks an effective treatment option. Early and …

[HTML][HTML] White-matter integrity on DTI and the pathologic staging of Alzheimer's disease

K Kantarci, ME Murray, CG Schwarz, RI Reid… - Neurobiology of …, 2017 - Elsevier
Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged
Alzheimer's disease (AD) patients (n= 46). Patients with antemortem DTI studies and a …

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

MÁ Araque Caballero, M Suárez-Calvet, M Duering… - Brain, 2018 - academic.oup.com
White matter alterations are present in the majority of patients with Alzheimer's disease type
dementia. However, the spatiotemporal pattern of white matter changes preceding dementia …

Aortic stiffness, increased white matter free water, and altered microstructural integrity: a continuum of injury

P Maillard, GF Mitchell, JJ Himali, A Beiser, E Fletcher… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Previous reports from the Framingham Heart Study have
identified cross-sectional associations of arterial stiffness, as reflected by carotid–femoral …

[HTML][HTML] Cholinergic white matter pathways make a stronger contribution to attention and memory in normal aging than cerebrovascular health and nucleus basalis of …

M Nemy, N Cedres, MJ Grothe, JS Muehlboeck… - Neuroimage, 2020 - Elsevier
The integrity of the cholinergic system plays a central role in cognitive decline both in normal
aging and neurological disorders including Alzheimer's disease and vascular cognitive …

Cholinergic white matter pathways along the Alzheimer's disease continuum

M Nemy, M Dyrba, F Brosseron, K Buerger, P Dechent… - Brain, 2023 - academic.oup.com
Previous studies have shown that the cholinergic nucleus basalis of Meynert and its white
matter projections are affected in Alzheimer's disease dementia and mild cognitive …

Age‐dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span

MÁA Caballero, Z Song, A Rubinski… - Alzheimer's & …, 2020 - Wiley Online Library
Abstract Introduction Both beta‐amyloid (Ab) deposition and decline in white matter integrity,
are brain alterations observed in Alzheimer's disease (AD) and start to occur by the fourth …

[HTML][HTML] Cognitive variability during middle-age: possible association with neurodegeneration and cognitive reserve

D Ferreira, A Machado, Y Molina, A Nieto… - Frontiers in aging …, 2017 - frontiersin.org
Objective: Increased variability in cognition with age has been argued as an indication of
pathological processes. Focusing on early detection of neurodegenerative disorders, we …

An efficient combination of quadruple biomarkers in binary classification using ensemble machine learning technique for early onset of Alzheimer disease

R Kumari, A Nigam, S Pushkar - Neural Computing and Applications, 2022 - Springer
BackgroundAlzheimer's disease (AD) is a degenerated condition of the brain where memory
loss is fully depleted for elderly individual. Efficient machine learning methods are …