Tripodi A, de Groot PG, Pengo V (IRCCS Cà Granda Ospedale Maggiore Policlinico
Foundation and Università degli Studi di Milano, Milan, Italy; Utrecht University Medical …

Antiphospholipid syndrome (APS) is an autoimmune condition that is associated with
thrombosis and morbidity in pregnancy. The exact mechanisms by which these associations …

New clinical, laboratory and experimental insights, since the 1999 publication of the
Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been …

Standardized enzyme-linked immunosorbent assays (ELISAs) for anticardiolipin (aCL) and
anti–2-glycoprotein I (anti-2GPI), though required for diagnosis of the antiphospholipid …

Objective. To identify factors predictive of significant neuropsychiatric (NP) damage in
systemic lupus erythematosus (SLE). Methods. One hundred and thirty patients with SLE …

The updated international consensus criteria for definite antiphospholipid syndrome (APS)
are useful for scientific clinical studies. However, there remains a need for diagnostic criteria …

In 1990, b2-glycoprotein I (b2-GPI) was shown to be the main protein cofactor involved in the
binding of antiphospholipid antibodies to anionic phospholipids [1–3]. The presence of b2 …

Current classification criteria for definite antiphospholipid syndrome (APS) mandate the use
of one or more of three positive 'standardized'laboratory assays to detect antiphospholipid …

The anticardiolipin (aCL) test has been widely used by physicians since the mid-1980s for
diagnosing patients with antiphospholipid syndrome (APS). Establishment of this diagnosis …

The antiphospholipid antibody syndrome (APS) is defined by two major elements: the
presence in plasma of auto‐antibodies, ie antiphospholipid antibodies and the occurrence …