Objective: In a recent report [Haynes et al. Science 2005; 308: 1906–1908], difficulties in
eliciting broadly neutralizing antibodies to HIV were linked to the binding of prototypic …

Anti-beta 2 glycoprotein 1 (anti-β2GP1) antibodies are commonly found in patients with
autoimmune diseases such as the antiphospholipid syndrome (APS) and systemic lupus …

Antiphospholipid antibodies are a wide and heterogeneous group of immunoglobulins that
include, among others, lupus anticoagulants and anticardiolipin antibodies. Their presence …

Consideration of the chronology of advances in medical knowledge can provide useful
insights into the pathogenesis, diagnosis and treatment of diseases. The antiphospholipid …

The aim of this study was to determine the prevalence and type of autoantibodies in a
general Australian population cohort. Samples collected from 198 individuals included in a …

The aim of this study was to evaluate the agreement in assay results between commercial
kits for the measurement of anti-β2glycoprotein I antibodies. Ten manufacturers provided …

The antiphospholipid syndrome (APS) is an autoimmune condition characterised by a wide
range of clinical features (primarily thrombosis and/or obstetric related), associated with the …

The antiphospholipid syndrome (APS) is an autoimmune condition characterized by
vascular thromboses and/or pregnancy morbidity, and its diagnosis currently requires …

Renal involvement can be a serious problem for patients with antiphospholipid syndrome
(APS). However, this complication has been poorly recognized and studied. It can be …

Despite the use of standardized GPL and MPL units, significant inter-laboratory and inter-
method variation in anticardiolipin antibody (aCL) testing still exists, limiting the clinical utility …