Angiogenesis in health and disease

P Carmeliet - Nature medicine, 2003 - nature.com
Blood vessels constitute the first organ in the embryo and form the largest network in our
body but, sadly, are also often deadly. When dysregulated, the formation of new blood …

Angiogenesis in life, disease and medicine

P Carmeliet - Nature, 2005 - nature.com
The growth of blood vessels (a process known as angiogenesis) is essential for organ
growth and repair. An imbalance in this process contributes to numerous malignant …

[HTML][HTML] Historical review of the causes of cancer

CB Blackadar - World journal of clinical oncology, 2016 - ncbi.nlm.nih.gov
In the early 1900s, numerous seminal publications reported that high rates of cancer
occurred in certain occupations. During this period, work with infectious agents produced …

A specialized vascular niche for adult neural stem cells

M Tavazoie, L Van der Veken, V Silva-Vargas… - Cell stem cell, 2008 - cell.com
Stem cells reside in specialized niches that regulate their self-renewal and differentiation.
The vasculature is emerging as an important component of stem cell niches. Here, we show …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Oncogenic effects of HIV-1 proteins, mechanisms behind

M Isaguliants, E Bayurova, D Avdoshina… - Cancers, 2021 - mdpi.com
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …

Infections and cancer: established associations and new hypotheses

C De Martel, S Franceschi - Critical reviews in oncology/hematology, 2009 - Elsevier
Around the world, infection is one of the most important causes of cancer. Almost one in
every five malignancies can be attributed to infectious agents. Among infection-related …

[HTML][HTML] Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent …

S Montaner, A Sodhi, A Molinolo, TH Bugge, ET Sawai… - Cancer cell, 2003 - cell.com
The Kaposi's sarcoma herpesvirus (KSHV) has been identified as the etiologic agent of
Kaposi's sarcoma (KS), but initial events leading to KS development remain unclear …

KSHV infection and the pathogenesis of Kaposi's sarcoma

D Ganem - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Kaposi's sarcoma (KS) has long been suspected of having an infectious etiology on the
basis of its unusual epidemiology, histopathology, and natural history. Nearly a decade ago …

[HTML][HTML] Tat is a multifunctional viral protein that modulates cellular gene expression and functions

E Clark, B Nava, M Caputi - Oncotarget, 2017 - ncbi.nlm.nih.gov
The human immunodeficiency virus type I (HIV-1) has developed several strategies to
condition the host environment to promote viral replication and spread. Viral proteins have …