Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

The potential role of cytokines and growth factors in the pathogenesis of Alzheimer's disease

G Ogunmokun, S Dewanjee, P Chakraborty… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prominent neurodegenerative diseases, which
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …

Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social …

FG Ibáñez, T Halvorson, K Sharma, CG McKee… - Brain, Behavior, and …, 2023 - Elsevier
Psychological stress confers an increased risk for several diseases including psychiatric
conditions. The susceptibility to psychological stress is modulated by various factors, many …

Cognitive impairment in long-COVID and its association with persistent dysregulation in inflammatory markers

RF Damiano, CCA Rocca, AP Serafim… - Frontiers in …, 2023 - frontiersin.org
Objective To analyze the potential impact of sociodemographic, clinical and biological
factors on the long-term cognitive outcome of patients who survived moderate and severe …

The multiple biotoxicity integrated study in grass carp (Ctenopharyngodon idella) caused by ochratoxin A: oxidative damage, apoptosis and immunosuppression

P Zhao, X Liu, WD Jiang, P Wu, Y Liu, J Jiang… - Journal of Hazardous …, 2022 - Elsevier
Ochratoxin A (OTA) is a common hazardous food contaminant that seriously endangers
human and animal health. However, limited study is focused on aquatic animal. This …

PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants

K Baysac, G Sun, H Nakano, EG Schmitz… - Journal of Allergy and …, 2024 - Elsevier
Background Pathogenic variants of phospholipase C gamma 2 (PLCG2) cause 2 related
forms of autosomal-dominant immune dysregulation (ID), PLCγ2-associated antibody …

Cytomodulatory characteristics of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) against cypermethrin on skin fibroblast cells (HFF-1)

S Aghajanshakeri, R Ataee, M Karami… - Toxicology, 2023 - Elsevier
The hematopoietic factor granulocyte macrophage-colony stimulating factor (GM-CSF) has
been identified via its capacity to promote bone marrow progenitors' development and …

Polymer-mediated Protein/Peptide Therapeutic Stabilization: Current Progress and Future Directions

RP Sivasankaran, K Snell, G Kunkel, P Georgiou… - Progress in Polymer …, 2024 - Elsevier
Proteins and peptides have played a pivotal role in revolutionizing disease treatment over
the last century. Despite their commercial success, protein therapeutics can be eliminated or …

[HTML][HTML] Potential of Neuroinflammation-Modulating Strategies in Tuberculous Meningitis: Targeting Microglia

HJ Lu, D Guo, QQ Wei - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Tuberculous meningitis (TBM) is the most severe complication of tuberculosis (TB) and is
associated with high rates of disability and mortality. Mycobacterium tuberculosis (M. tb), the …

Macrophages: A rising star in immunotherapy for chronic pancreatitis

H Xiang, H Yu, Q Zhou, Y Wu, J Ren, Z Zhao… - Pharmacological …, 2022 - Elsevier
Chronic pancreatitis (CP) is a chronic wasting disease with an increasing incidence. As an
important factor in the pathogenesis of CP, macrophages play a considerable role in the …