Pericytes of the neurovascular unit: key functions and signaling pathways
MD Sweeney, S Ayyadurai, BV Zlokovic - Nature neuroscience, 2016 - nature.com
Pericytes are vascular mural cells embedded in the basement membrane of blood
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …
[HTML][HTML] Pericytes: developmental, physiological, and pathological perspectives, problems, and promises
A Armulik, G Genové, C Betsholtz - Developmental cell, 2011 - cell.com
Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …
of vascular morphogenesis and function during development, cardiovascular homeostasis …
[HTML][HTML] Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes
The precise regulation of cerebral blood flow is critical for normal brain function, and its
disruption underlies many neuropathologies. The extent to which smooth muscle-covered …
disruption underlies many neuropathologies. The extent to which smooth muscle-covered …
[HTML][HTML] The inner blood-retinal barrier: Cellular basis and development
M Díaz-Coránguez, C Ramos, DA Antonetti - Vision research, 2017 - Elsevier
The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining
proper neural homeostasis and protecting the neural tissue from potential blood borne …
proper neural homeostasis and protecting the neural tissue from potential blood borne …
[HTML][HTML] Plastic roles of pericytes in the blood–retinal barrier
The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells
covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully …
covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully …
[HTML][HTML] The CLDN5 gene at the blood-brain barrier in health and disease
Y Hashimoto, C Greene, A Munnich… - Fluids and Barriers of the …, 2023 - Springer
The CLDN5 gene encodes claudin-5 (CLDN-5) that is expressed in endothelial cells and
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …
forms tight junctions which limit the passive diffusions of ions and solutes. The blood–brain …
[HTML][HTML] Intraventricular hemorrhage in premature infants: mechanism of disease
P Ballabh - Pediatric research, 2010 - nature.com
Intraventricular hemorrhage (IVH) is a major complication of prematurity. IVH typically
initiates in the germinal matrix, which is a richly vascularized collection of neuronal-glial …
initiates in the germinal matrix, which is a richly vascularized collection of neuronal-glial …
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
HG Augustin, G Young Koh, G Thurston… - Nature reviews Molecular …, 2009 - nature.com
Angiogenesis, the growth of blood vessels, is a fundamental biological process that controls
embryonic development and is also involved in numerous life-threatening human diseases …
embryonic development and is also involved in numerous life-threatening human diseases …
[HTML][HTML] VEGFR1 signaling in retinal angiogenesis and microinflammation
Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …
Molecular regulation of vessel maturation
RK Jain - Nature medicine, 2003 - nature.com
The maturation of nascent vasculature, formed by vasculogenesis or angiogenesis, requires
recruitment of mural cells, generation of an extracellular matrix and specialization of the …
recruitment of mural cells, generation of an extracellular matrix and specialization of the …