Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract
T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development
MM Zhao, WL Yang, FY Yang, L Zhang… - Signal transduction and …, 2021 - nature.com
To discover new drugs to combat COVID-19, an understanding of the molecular basis of
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
[PDF][PDF] Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
Lifting the mask on neurological manifestations of COVID-19
A Pezzini, A Padovani - Nature Reviews Neurology, 2020 - nature.com
As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic spreads, it
is becoming increasingly evident that coronavirus disease 2019 (COVID-19) is not limited to …
is becoming increasingly evident that coronavirus disease 2019 (COVID-19) is not limited to …
The trinity of COVID-19: immunity, inflammation and intervention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
X Ou, Y Liu, X Lei, P Li, D Mi, L Ren, L Guo… - Nature …, 2020 - nature.com
Abstract Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks,
SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late …
SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late …
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started
to circulate among humans around December 2019, and it is now widespread as a global …
to circulate among humans around December 2019, and it is now widespread as a global …
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
D Bestle, MR Heindl, H Limburg… - Life science …, 2020 - life-science-alliance.org
The novel emerged SARS-CoV-2 has rapidly spread around the world causing acute
infection of the respiratory tract (COVID-19) that can result in severe disease and lethality …
infection of the respiratory tract (COVID-19) that can result in severe disease and lethality …
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
S Boopathi, AB Poma, P Kolandaivel - Journal of Biomolecular …, 2021 - Taylor & Francis
In the past two decades, the world has faced several infectious disease outbreaks. Ebola,
Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms …
Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms …