Coronavirus membrane fusion mechanism offers a potential target for antiviral development
Abstract The coronavirus disease 2019 (COVID-19) pandemic has focused attention on the
need to develop effective therapies against the causative agent, SARS-CoV-2, and also …
need to develop effective therapies against the causative agent, SARS-CoV-2, and also …
Natural product-derived phytochemicals as potential agents against coronaviruses: A review
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
R Yan, Y Zhang, Y Li, L Xia, Y Guo, Q Zhou - Science, 2020 - science.org
Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing …
Severe acute respiratory syndrome: historical, epidemiologic, and clinical features
Over the past 2 decades 2 previously unknown coronaviruses (CoVs), the severe acute
respiratory syndrome CoV (SARS-CoV) and the Middle East respiratory syndrome CoV …
respiratory syndrome CoV (SARS-CoV) and the Middle East respiratory syndrome CoV …
Nanotechnology for COVID-19: therapeutics and vaccine research
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …
an urgent deployment of advanced therapeutic options available. The role of …
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity
M Hoffmann, H Hofmann-Winkler, JC Smith… - …, 2021 - thelancet.com
Background Antivirals are needed to combat the COVID-19 pandemic, which is caused by
SARS-CoV-2. The clinically-proven protease inhibitor Camostat mesylate inhibits SARS …
SARS-CoV-2. The clinically-proven protease inhibitor Camostat mesylate inhibits SARS …
[PDF][PDF] Multi-organ proteomic landscape of COVID-19 autopsies
X Nie, L Qian, R Sun, B Huang, X Dong, Q Xiao… - Cell, 2021 - cell.com
The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
Drug targets for corona virus: A systematic review
M Prajapat, P Sarma, N Shekhar, P Avti… - Indian journal of …, 2020 - journals.lww.com
Abstract The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21 th
century. However, the lack of specific drugs to prevent/treat an attack is a major need at this …
century. However, the lack of specific drugs to prevent/treat an attack is a major need at this …
[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?
M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …
Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
S Matsuyama, N Nao, K Shirato… - Proceedings of the …, 2020 - National Acad Sciences
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently …
which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently …