A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and
constitute a superfamily consisting of more than 100 members. This superfamily is …

The synapsins are a family of neuronal phosphoproteins evolutionarily conserved in
invertebrate and vertebrate organisms. Their best-characterised function is to modulate …

SNARE proteins have been proposed to mediate all intracellular membrane fusion events.
There are over 30 SNARE family members in mammalian cells and each is found in a …

The testicular spermatozoa of all mammalian species are considered functionally immature
owing to their inability to swim in a progressive manner and engage in productive …

Stimulus-secretion coupling is an essential process in secretory cells in which regulated
exocytosis occurs, including neuronal, neuroendocrine, endocrine, and exocrine cells. While …

Phagosomes are key organelles for the innate ability of macrophages to participate in tissue
remodeling, clear apoptotic cells, and restrict the spread of intracellular pathogens. To …

Synaptic vesicle fusion at synapses is triggered by increases in cytosolic Ca 2+ levels.
However, the identity of the Ca 2+ sensor and the transduction mechanism of the Ca 2+ …

This is an innovative and engaging companion to the language of memory research. It
consists of over 130 entries, bound within a coherent conceptual framework. Each entry …

During neurotransmitter release, the neuronal SNARE proteins synaptobrevin/VAMP,
syntaxin, and SNAP-25 form a four-helix bundle, the SNARE complex, that pulls the synaptic …