Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
Adult neurogenesis in Alzheimer's disease
SH Choi, RE Tanzi - Hippocampus, 2023 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of age‐related dementia, characterized
by progressive memory loss and cognitive disturbances. The hippocampus, where adult …
by progressive memory loss and cognitive disturbances. The hippocampus, where adult …
[HTML][HTML] Alzheimer's disease: from pathogenesis to mesenchymal stem cell therapy–bridging the missing link
J Hu, X Wang - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide. With
the increasing trend of population aging, the estimated number of AD continues to climb …
the increasing trend of population aging, the estimated number of AD continues to climb …
Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer's disease
J Chang, Y Li, X Shan, X Chen, X Yan… - Neural Regeneration …, 2024 - journals.lww.com
Recent studies have demonstrated that neuroplasticity, such as synaptic plasticity and
neurogenesis, exists throughout the normal lifespan but declines with age and is …
neurogenesis, exists throughout the normal lifespan but declines with age and is …
[HTML][HTML] Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain
CS Norevik, AM Huuha, RN Røsbjørgen… - Journal of Sport and …, 2024 - Elsevier
Background Exercise training promotes brain plasticity and is associated with protection
against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be …
against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be …
[HTML][HTML] Long-lasting restoration of memory function and hippocampal synaptic plasticity by focused ultrasound in Alzheimer's disease
Background Focused ultrasound (FUS) is a medical technology that non-invasively
stimulates the brain and has been applied in thermal ablation, blood–brain barrier (BBB) …
stimulates the brain and has been applied in thermal ablation, blood–brain barrier (BBB) …
Alzheimer's disease: challenges and a therapeutic opportunity to treat it with a neurotrophic compound
N Baazaoui, K Iqbal - Biomolecules, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease with an insidious
onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are …
onset and multifactorial nature. A deficit in neurogenesis and synaptic plasticity are …
[PDF][PDF] Inhibitors of Intracellular Signaling Molecules: New Horizons in Drug Discovery for the Treatment of Alzheimer's Disease
GN Zyuz'kov, LA Miroshnichenko… - … research in applied …, 2023 - biointerfaceresearch.com
Alzheimer's disease (AD) is a prime example of a pathology with extremely low treatment
efficiency. The relevance of developing new drugs for its treatment is beyond doubt. Modern …
efficiency. The relevance of developing new drugs for its treatment is beyond doubt. Modern …
[HTML][HTML] Hippocampal atrophy is associated with hearing loss in cognitively normal adults
YJ Shim, WH Jung, AJ Billig, W Sedley… - Frontiers in …, 2023 - frontiersin.org
Objectives A growing body of evidence suggests that age-related hearing loss (HL) is
associated with morphological changes of the cerebral cortex, but the results have been …
associated with morphological changes of the cerebral cortex, but the results have been …
Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease
SB Arredondo, DT Reyes, A Herrera-Soto… - Scientific Reports, 2021 - nature.com
In Alzheimer´ s disease (AD) there is a reduction in hippocampal neurogenesis that has
been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO) …
been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO) …