[HTML][HTML] Tumor microenvironment complexity and therapeutic implications at a glance

R Baghban, L Roshangar… - Cell Communication and …, 2020 - Springer
The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …

[HTML][HTML] Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

[HTML][HTML] Salivary biomarkers for oral squamous cell carcinoma diagnosis and follow-up: current status and perspectives

M Cristaldi, R Mauceri, O Di Fede, G Giuliana… - Frontiers in …, 2019 - frontiersin.org
Oral cancer is the sixth most common cancer type in the world, and 90% of it is represented
by oral squamous cell carcinoma (OSCC). Despite progress in preventive and therapeutic …

[HTML][HTML] Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

[HTML][HTML] Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies

S Wang, K Zhang, S Tan, J Xin, Q Yuan, H Xu, X Xu… - Molecular cancer, 2021 - Springer
Cancer is a leading cause of death worldwide, particularly because of its high mortality rate
in patients who are diagnosed at late stages. Conventional biomarkers originating from …

[HTML][HTML] Peripheral blood-based biomarkers for immune checkpoint inhibitors

HJ An, HJ Chon, C Kim - International journal of molecular sciences, 2021 - mdpi.com
As cancer immunotherapy using immune checkpoint inhibitors (ICIs) is rapidly evolving in
clinical practice, it is necessary to identify biomarkers that will allow the selection of cancer …

Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer

WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas… - European urology, 2019 - Elsevier
Background Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the
disease. Several recent studies have identified genomic alterations in mCRPC, but the …

[HTML][HTML] Liquid biopsy in oral cancer

F Lousada-Fernandez, O Rapado-Gonzalez… - International journal of …, 2018 - mdpi.com
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a
complex process, in which heterogeneity plays an important role in the development and …

[HTML][HTML] Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

J Li, X Han, X Yu, Z Xu, G Yang, B Liu, P Xiu - Journal of Experimental & …, 2018 - Springer
Hepatocellular carcinoma (HCC) is a highly malignant disease with a poor prognosis and
high mortality due to a low early diagnosis rate, resistance to systemic treatments and …

[HTML][HTML] Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA

MA Kerachian, M Azghandi, S Mozaffari-Jovin… - Clinical …, 2021 - Springer
Methylation analysis of circulating cell-free DNA (cirDNA), as a liquid biopsy, has a
significant potential to advance the detection, prognosis, and treatment of cancer, as well as …