Rhesus is the clinically most important protein-based blood group system. It represents the
largest number of antigens and the most complex genetics of the 30 known blood group …

Genomics is affecting all areas of medicine. In transfusion medicine, DNA-based genotyping
is being used as an alternative to serological antibody-based methods to determine blood …

After reviewing the relative frequency of the causes of allogeneic blood transfusion-related
mortality in the United States today, we present 6 possible strategies for further reducing …

Each year, blood transfusions save millions of lives. However, under current blood-matching
practices, sensitization to non–self-antigens is an unavoidable adverse side effect of …

BACKGROUND: A “BeadChip” array permits reliable simultaneous DNA typing of single‐
nucleotide polymorphisms for minor blood groups. A high‐throughput DNA analysis was …

Blood group antigens, present on the cell membrane of red blood cells and platelets, can be
defined either serologically or predicted based on the genotypes of genes encoding for …

BACKGROUND: Traditionally, transfusion medicine, platelet and human leukocyte antigen
(HLA) typing, and forensic medicine relied on serologic studies. METHODS: In recent years …

The molecular background of blood group antigen expression of the major clinically
significant blood group antigens has been largely accomplished. Despite this large body of …

summary In order to determine gene frequencies of human platelet antigen (HPA) and
establish a panel of accredited HPA‐1a,‐2a,‐4a,‐5a and‐6a‐negative donors as well as an …

Background Blood samples from patients with sickle cell disease (SCD) present to
transfusion service with numerous antibodies, making the searching for compatible red …