CD8+ T cells are activated by TCRs that recognize specific cognate Ags, while NK-cell
activation is regulated by a balance between signals from germline-encoded activating and …

Being among the top 10 causes of adult deaths, tuberculosis (TB) disease is considered a
major global public health concern to address. The human tuberculosis pathogen …

Macaques provide the most widely used nonhuman primate models for studying the
immunology and pathogenesis of human diseases. Although the macaque major …

Abstract Characterization of immune cells is essential to advance our understanding of
immunology and flow cytometry is an important tool in this context. Addressing both cellular …

The extent to which unconventional forms of antigen presentation drive T cell immunity is
unknown. By convention, CD8 T cells recognize viral peptides, or epitopes, in association …

Post-transplant cyclophosphamide (PTCy) is becoming the standard prophylaxis for graft-
versus-host disease (GVHD) in HLA-haploidentical allogeneic hematopoietic cell …

The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E
(HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability …

Naturally occurring T cells that recognize microbial peptides via HLA-E, a nonpolymorphic
HLA class Ib molecule, could provide the foundation for new universal immunotherapeutics …

HLA-E molecules can present self-and pathogen-derived peptides to both natural killer (NK)
cells and T cells. T cells that recognize HLA-E peptides via their T cell receptor (TCR) are …

Over the past decades, many drugs based on the use of nanotechnology and nucleic acids
have been developed. However, until recently, most of them remained at the stage of pre …