Natural products (NPs) are primarily recognized as privileged structures to interact with
protein drug targets. Their unique characteristics and structural diversity continue to marvel …

Network pharmacology is an emerging area of systematic drug research that attempts to
understand drug actions and interactions with multiple targets. Network pharmacology has …

Coronavirus disease strain (SARS-CoV-2) was discovered in 2019, and it is spreading very
fast around the world causing the disease Covid-19. Currently, more than 1.6 million …

Informatics is growing across disciplines, impacting several areas of chemistry, biology, and
biomedical sciences. Besides the well-established bioinformatics discipline, other …

Highlights•Natural products show great promises in the drug repositioning campaign.•New
drug-disease associations are uncovered and discussed.•Pros and cons in natural product …

The interactions of two crucial proteins of COVID-19 have been investigated with potential
antiviral compounds from Moringa oliefera using quantum chemical, molecular docking and …

Deep reinforcement learning methods have been shown to be potentially powerful tools for
de novo design. Recurrent-neural-network-based techniques are the most widely used …

Stroke is a fatal cerebral vascular disease with a high mortality rate and substantial
economic and social costs. ROS production and neuroinflammation have been implicated in …

Background Coronaviruses are responsible for several human diseases, such as the
infectious novel coronavirus disease 2019 (COVID-19), which is caused by severe acute …

The convergence of biology and computational science has ushered in a revolutionary era,
revolutionizing our understanding of biological systems and providing novel solutions to …