[HTML][HTML] The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

[HTML][HTML] Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease

SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …

[HTML][HTML] Rapid syndromic PCR testing in patients with respiratory tract infections reduces time to results and improves microbial yield

S Serigstad, D Markussen, HMS Grewal, M Ebbesen… - Scientific Reports, 2022 - nature.com
Lack of rapid and comprehensive microbiological diagnosis in patients with community
acquired pneumonia (CAP) hampers appropriate antimicrobial therapy. This study evaluates …

The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

[HTML][HTML] SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections

F Cyprian, MU Sohail, I Abdelhafez, S Salman… - International Journal of …, 2021 - Elsevier
By the beginning of 2020, infection caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an …

[HTML][HTML] The lung microbiome: A new frontier for lung and brain disease

J Chen, T Li, C Ye, J Zhong, JD Huang, Y Ke… - International Journal of …, 2023 - mdpi.com
Due to the limitations of culture techniques, the lung in a healthy state is traditionally
considered to be a sterile organ. With the development of non-culture-dependent …

The airway microbiome in COPD, bronchiectasis and bronchiectasis‐COPD overlap

PY Tiew, TK Jaggi, LLY Chan… - The Clinical …, 2021 - Wiley Online Library
Objective To review the airway microbiome in chronic obstructive pulmonary disease
(COPD), bronchiectasis and bronchiectasis‐COPD overlap (BCO). Data source and study …

[HTML][HTML] Effects of tea against alcoholic fatty liver disease by modulating gut microbiota in chronic alcohol-exposed mice

B Li, Q Mao, D Zhou, M Luo, R Gan, H Li, S Huang… - Foods, 2021 - mdpi.com
Gut microbiota dysbiosis has been a crucial contributor to the pathogenesis of alcoholic fatty
liver disease (AFLD). Tea is a popular beverage worldwide and exerts antioxidant and anti …

Prevalence and 30-day mortality in hospitalized patients with Covid-19 and prior lung diseases

J Signes-Costa, IJ Nunez-Gil, JB Soriano… - Archivos de …, 2021 - Elsevier
Introduction Patients with pre-existing respiratory diseases in the setting of COVID-19 may
have a greater risk of severe complications and even death. Methods A retrospective …

[HTML][HTML] Impact of lung microbiota on COPD

C Russo, V Colaianni, G Ielo, MS Valle, L Spicuzza… - Biomedicines, 2022 - mdpi.com
There is a fine balance in maintaining healthy microbiota composition, and its alterations
due to genetic, lifestyle, and environmental factors can lead to the onset of respiratory …