The nucleotide-binding, oligomerization domain-like receptor family pyrin domain containing
3 (NLRP3) inflammasome is a multiprotein complex that combines sensing, regulation, and …

NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

Almost all human diseases are strongly associated with inflammation, and a deep
understanding of the exact mechanism is helpful for treatment. The NLRP3 inflammasome …

NLRP3 (NOD-like receptor pyrin domain-containing protein 3) is an innate immune sensor
that contributes to the development of different diseases, including monogenic …

Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

The prevalence of neurodegenerative disease has increased significantly in recent years,
and with a rapidly aging global population, this trend is expected to continue. These …

Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to
further injury that contributes to the final infarct size. Locally released danger-associated …

Adenosine triphosphate (ATP) is a molecule that on one hand plays a central role in cellular
energetics and which on the other is a ubiquitous signaling molecule when released into the …

Nucleotide-binding, oligomerization domain (NOD)-like receptor family, pyrin domain
containing 3 (NLRP3) gene polymorphism was reported to be associated with susceptibility …

Systemic autoinflammatory diseases (SAIDs) are a growing group of disorders caused by a
dysregulation of the innate immune system leading to episodes of systemic inflammation. In …