The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

Antioxidants are molecules that delay or inhibit the oxidation of other molecules. Its use
significantly increased in recent years in the diet of people. Natural antioxidants are …

Introduction: Aging is a normal, inevitable, irreversible and progressive process which is
driven by internal and external factors. Oxidative stress, that is the imbalance between …

The TP53 tumor suppressor gene is the most frequently altered gene in tumors and an
increasing number of studies highlight that mutant p53 proteins can acquire oncogenic …

The failure in effective cancer treatment is thought to be attributed to a subpopulation of
tumor cells with stem cell-like properties. These cancer stem cells (CSCs) are intimately …

The ability of solar ultraviolet (UV) to induce skin cancer and photoaging is well recognized.
The effect of the infrared (IR) and visible light (Vis) components of solar radiation on skin and …

Skin ageing is the result of a loss of cellular function, which can be further accelerated by
external factors. Mitochondria have important roles in skin function, and mitochondrial …

Autoimmune disorders are distinct with over production and accumulation of free radicals
due to its undisclosed genesis. The cause of numerous disorders as cancer, arthritis …

Oxidative stress and its end-products, such as 4-hydroxynonenal (HNE), initiate activation of
the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)/Kelch Like ECH Associated Protein …