Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …

Multiple sclerosis (MS), a debilitating autoimmune inflammatory disease that affects the
brain and spinal cord, causes demyelination of neurons, axonal damage, and …

Introduction Multiple sclerosis (MS) is the most frequent demyelinating disease of the central
nervous system. Although there is currently there is no definite cure for MS, new therapies …

Multiple sclerosis (MS) is a complex disease of the central nervous system (CNS) that
involves an intricate and aberrant interaction of immune cells leading to inflammation …

Multiple sclerosis is a highly complex and heterogeneous disease. At the onset it often
presents as a clinically isolated syndrome. Thereafter relapses are followed by periods of …

Introduction Recent works demonstrate that patients with multiple sclerosis (pwMS) and
oligoclonal M bands (OCMB) in cerebrospinal fluid (CSF) are at higher risk of conversion to …

Background Emerging evidence supports that determination of intrathecal immunoglobulin
M (IgM) synthesis (ITMS) and neurofilament light (NfL) concentration in cerebrospinal fluid …

The presence of intrathecal IgM synthesis (ITMS) has been associated with an aggressive
multiple sclerosis (MS) clinical course. In the present systematic review, we aimed at …

Background Distinguishing between MOG-associated disease (MOGAD) and multiple
sclerosis (MS) presents a considerable challenge, as there are instances of overlapping …

Cerebrospinal kappa free light chain (KFLC)-index is a marker of intrathecal
immunoglobulin synthesis that aids in the diagnosis of multiple sclerosis (MS). However …