Cancer initiation and progression is an accumulation of genetic and epigenetic
modifications. DNA methylation is a common epigenetic modification that regulates gene …

Background Folic acid and its derivates, known as folates, are chemoprotective
micronutrients of great interest because of their essential role in the maintenance of health …

Inflammation and oxidative stress (OS) are key points in age progression. Both processes
impact negatively in cognition and in brain functions. Resveratrol (RV) has been postulated …

Ethanol is well known as a teratogenic factor that is capable of inducing a wide range of
developmental abnormalities if the developing fetus is exposed to it. Duration and dose are …

Background: Global DNA methylation has an impact in cancer pathogenesis and
progression. This study aimed at investigating the impact of global DNA methylation in …

Background It has been reported that paternal folic acid deficiency is correlated with male
infertility and increased birth defects in the offspring. However, there are few data …

Gene expression altering epigenomic modifications such as DNA methylation, histone
modification, and chromosome remodeling is crucial to regulating many biological …

Ethanol is well known for its teratogenic effects during fetal development. Maternal alcohol
consumption allows the developing fetus to experience the detrimental effects of alcohol …

Growing evidence suggests that arsenic exposure increases the risk of developing a variety
of inflammation-associated chronic diseases and cancers. Our previous study revealed that …

Folate is a vital vitamin involved in one-carbon metabolism and any changes in folate status
may lead to epigenetic alterations. It is already known that stages and liver cancer …