Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

[HTML][HTML] Ischemia/reperfusion

T Kalogeris, CP Baines, M Krenz… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Biological effects of indole-3-propionic acid, a gut microbiota-derived metabolite, and its precursor tryptophan in mammals' health and disease

P Konopelski, I Mogilnicka - International journal of molecular sciences, 2022 - mdpi.com
Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with age-related comorbidities–role of gut microbiota dysbiosis

SD Viana, S Nunes, F Reis - Ageing research reviews, 2020 - Elsevier
Abstract Coronavirus disease 19 (COVID-19) is a pandemic condition caused by the new
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …

Dietary polyphenols to combat the metabolic diseases via altering gut microbiota

V Gowd, N Karim, MRI Shishir, L Xie, W Chen - Trends in Food Science & …, 2019 - Elsevier
Abstract Background Metabolic syndrome (MetS) is defined as the cluster of metabolic
disorders that consist of insulin resistance, hyperglycemia, dyslipidemia, central adiposity …

Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets

YK Tham, BC Bernardo, JYY Ooi, KL Weeks… - Archives of …, 2015 - Springer
The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Gut–organ axis: a microbial outreach and networking

S Ahlawat, Asha, KK Sharma - Letters in applied microbiology, 2021 - academic.oup.com
Human gut microbiota (GM) includes a complex and dynamic population of microorganisms
that are crucial for well‐being and survival of the organism. It has been reported as diverse …

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

LS Zhang, SS Davies - Genome medicine, 2016 - Springer
Mass spectrometry-and nuclear magnetic resonance-based metabolomic studies comparing
diseased versus healthy individuals have shown that microbial metabolites are often the …