Sphingolipids are essential components of all eukaryotic membranes. The bioactive
sphingolipid molecule, Sphingosine 1-Phosphate (S1P), regulates various important …

Behçet's disease (BD) is a chronic systemic vasculitis characterized by recurrent oral and
genital ulcers, skin lesions, articular, neurological, vascular and sight-threatening ocular …

Neutrophil extracellular traps (NETs) are involved in the activation and dysfunction of
multiple overlapping and interacting pathways, including the immune response to injury …

Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs),
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …

Sepsis currently remains a major contributor to mortality in the intensive care unit (ICU), with
48.9 million cases reported globally and a mortality rate of 22.5% in 2017, accounting for …

Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …

BACKGROUND: Neutrophil extracellular traps (NETs) are composed of DNA, enzymes, and
citrullinated histones that are expelled by neutrophils in the process of NETosis. NETs …

NIK plays a crucial role in the noncanonical NF-κB signaling pathway associated with
diverse inflammatory and autoimmune diseases. Our study presents compound 54, a novel …

While neutrophil extracellular traps (NETs) have previously been linked to some diabetes-
associated complications, such as dysfunctional wound healing, their potential role in …

Vascular endothelial cells (ECs), the inner layer of blood vessels, were previously
considered to be a passive lining that facilitates cellular and molecular exchange. However …