One of the objectives of metabonomics is to identify subtle changes in metabolite profiles
between biological systems of different physiological or pathological states. Gas …

An overview of the use of CE‐MS in the field of metabolomics is provided. Metabolomics is
concerned with the comprehensive analysis of endogenous low‐molecular‐weight …

Social bees harbor a simple and specialized microbiota that is spatially organized into
different gut compartments. Recent results on the potential involvement of bee gut …

Gas chromatography–mass spectrometry (GC‐MS)–based metabolomics is ideal for
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …

Psychiatric disorders are characterized by major fluctuations in psychological function over
the course of weeks and months, but the dynamic characteristics of brain function over this …

Patients and animals with chronic kidney disease (CKD) exhibit profound alterations in the
gut environment including shifts in microbial composition, increased fecal pH, and increased …

Insulin resistance progressing to type 2 diabetes mellitus (T2DM) is marked by a broad
perturbation of macronutrient intermediary metabolism. Understanding the biochemical …

Recent progress in metabolomics and the development of increasingly sensitive analytical
techniques have renewed interest in global profiling, ie, semiquantitative monitoring of all …

Understanding the regulation of islet cell mass has important implications for the discovery
of regenerative therapies for diabetes. The liver plays a central role in metabolism and the …

We have reviewed the main contributions to the development of NMR-based metabonomic
and metabolic profiling approaches for toxicological assessment, biomarker discovery, and …