Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …
[HTML][HTML] A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population
JM Delgado-Saborit, V Guercio, AM Gowers… - Science of the Total …, 2021 - Elsevier
Dementia is arguably the most pressing public health challenge of our age. Since dementia
does not have a cure, identifying risk factors that can be controlled has become paramount …
does not have a cure, identifying risk factors that can be controlled has become paramount …
Heavy metals exposure and Alzheimer's disease and related dementias
KM Bakulski, YA Seo, RC Hickman… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
Association between heavy metal exposure and Parkinson's disease: a review of the mechanisms related to oxidative stress
Parkinson's disease (PD) is a gradually progressing neurodegenerative condition that is
marked by a loss of motor coordination along with non-motor features. Although the precise …
marked by a loss of motor coordination along with non-motor features. Although the precise …
Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
IM Carey, HR Anderson, RW Atkinson, SD Beevers… - BMJ open, 2018 - bmjopen.bmj.com
Objective To investigate whether the incidence of dementia is related to residential levels of
air and noise pollution in London. Design Retrospective cohort study using primary care …
air and noise pollution in London. Design Retrospective cohort study using primary care …
Role of environmental contaminants in the etiology of Alzheimer's disease: a review
M Yegambaram, B Manivannan… - Current Alzheimer …, 2015 - ingentaconnect.com
Alzheimer's dis ease (AD) is a leading cause of mortality in the developed world with 70%
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …
A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line
Literature on maternal exposures and the risk of epigenetic changes or diseases in the
offspring is growing. Paternal contributions are often not considered. However, some animal …
offspring is growing. Paternal contributions are often not considered. However, some animal …
Targeting epigenetics: A novel promise for Alzheimer's disease treatment
D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing Research Reviews, 2023 - Elsevier
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
[HTML][HTML] Doença de Alzheimer: hipóteses etiológicas e perspectivas de tratamento
With the increase in life expectancy registered in the past few decades, the prevalence of
various medical conditions related to aging has been observed, such as dementia and …
various medical conditions related to aging has been observed, such as dementia and …
Emerging risk of environmental factors: insight mechanisms of Alzheimer's diseases
Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …
influenced through an extensive range of environmental factors, lifestyle, and genetic …