Estimation of target occupancy in repeated dosing design studies using positron emission tomography: Biases due to target upregulation
EA Rabiner, RN Gunn - Journal of Cerebral Blood Flow & …, 2024 - journals.sagepub.com
Positron emission tomography (PET) has become indispensable in the quantification of
target engagement by brain targeting medications. The relationship between the drug …
target engagement by brain targeting medications. The relationship between the drug …