Primary cultures of diploid fibroblasts give rise to populations which have limited growth
potential. In the ca se of human cells, their in vitro life span is usually in the range of 50-70 …

A synopsis will be presented of work on DNA methylation, the first epigenetic signal to be
recognized. In the author´ s laboratory, the following problems dealing with DNA methylation …

Homologies between spinach nuclear (n) DNA and Chloroplast (pt) DNA, have been
detected with a clone bank of spinach ptDNA as hybridization probes to restriction fragments …

Patterns of DNA methylation in complex genomes like those of mammalian cells have been
viewed as indicators of different levels of genetic activities. It is as yet unknown how these …

Abstract Frog virus 3 (FV3) DNA is the most highly methylated DNA of any known DNA virus;
about 20% of the cytosine residues in FV3 DNA are methylated (D. Willis and A. Granoff …

Five plaque-forming viruses (Pbi viruses) of the unicellular, eukaryotic, exsymbiotic Chlorella-
like green alga strain Pbi were isolated from fresh water collected in Germany. The viruses …

Publisher Summary This chapter discusses DNA methylation in eukaryotic cells. DNA
methylation pattern undergoes discrete changes, especially during the process of …

We have shown previously that the EBNA 1 and latent membrane protein encoding regions
of the Epstein—Barr virus (EBV) genome are highly methylated at CCGG sequences in the …

Methylation of CCGG sites was examined in four regions of the X chromosome with four X‐
chromosome clones, three obtained by cloning random segments and one encoding a …

A shooty tumor induced by a shooter mutant of an octopine strain of Agrobacterium
tumefaciens was cloned. One clone obtained (TS038) behaved aberrantly in that it grew as …