Adherence to continuous positive airway pressure therapy: the challenge to effective treatment

TE Weaver, RR Grunstein - Proceedings of the American Thoracic …, 2008 - atsjournals.org
Despite the high efficacy of continuous positive airway pressure (CPAP) to reverse upper
airway obstruction in sleep apnea, treatment effectiveness is limited by variable adherence …

Gender differences in sleep disorders

V Krishnan, NA Collop - Current opinion in pulmonary medicine, 2006 - journals.lww.com
Gender differences in sleep become apparent after the onset of puberty. Menstrual cycles,
pregnancy, and menopause can alter sleep architecture. Gender-related differences in …

Patient adherence and medical treatment outcomes: a meta-analysis

MR DiMatteo, PJ Giordani, HS Lepper… - Medical care, 2002 - journals.lww.com
Background. Adherence is a factor in the outcome of medical treatment, but the strength and
moderators of the adherence-outcome association have not been systematically assessed …

Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome

S Ryan, CT Taylor, WT McNicholas - Circulation, 2005 - Am Heart Assoc
Background—Obstructive sleep apnea syndrome (OSAS), characterized by intermittent
hypoxia/reoxygenation (IHR), is an independent risk factor for cardiovascular disease. We …

Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders

CA Kushida, MR Littner, M Hirshkowitz… - Sleep, 2006 - academic.oup.com
Positive airway pressure (PAP) devices are used to treat patients with sleep related
breathing disorders (SRBD) including obstructive sleep apnea (OSA). Currently, PAP …

Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome

N Mcardle, G Devereux, H Heidarnejad… - American journal of …, 1999 - atsjournals.org
Patients with the sleep apnea/hypopnea syndrome (SAHS) treated by nasal continuous
positive airway pressure (CPAP) need to use CPAP long-term to prevent recurrence of …

Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults

P Gay, T Weaver, D Loube, C Iber - Sleep, 2006 - academic.oup.com
Positive airway pressure (PAP) is used to treat obstructive sleep apnea (OSA), central sleep
apnea (CSA), and chronic hypoventilation. This document provides a systematic analysis …

Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS)

HM Engleman, MR Wild - Sleep medicine reviews, 2003 - Elsevier
Though continuous positive airway pressure (CPAP) is the treatment of choice for the sleep
apnoea/hypopnoea syndrome (SAHS), suboptimal adherence to CPAP is common …

The Italian multicentre study on noninvasive ventilation in chronic obstructive pulmonary disease patients

E Clini, C Sturani, A Rossi, S Viaggi… - European …, 2002 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) patients with chronic ventilatory failure
(CVF) are more likely to develop exacerbations, which are an important determinant of …

Molecular signatures of obstructive sleep apnea in adults: a review and perspective

ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …