MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic
liver disease globally and is currently estimated to affect up to 38% of the global adult …
liver disease globally and is currently estimated to affect up to 38% of the global adult …
NAFLD and NASH: etiology, targets and emerging therapies
S Wei, L Wang, PC Evans, S Xu - Drug Discovery Today, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) pose a
significant threat to human health and cause a tremendous socioeconomic burden …
significant threat to human health and cause a tremendous socioeconomic burden …
Quantitative imaging reveals steatosis and fibro-inflammation in multiple organs in people with type 2 diabetes: a real-world study.
We aimed to determine the extent of multi-organ fat accumulation and fibro-inflammation in
individuals living with type 2 diabetes. We deeply phenotyped individuals with type 2 …
individuals living with type 2 diabetes. We deeply phenotyped individuals with type 2 …
New horizons in the diagnosis and management of patients with MASLD
KJ van Erpecum, GN Dalekos - European Journal of Internal Medicine, 2024 - ejinme.com
The collection'New horizons in the diagnosis and management of patients with metabolic
dysfunction-associated steatotic liver disease (MASLD)'that is presented here, deals with the …
dysfunction-associated steatotic liver disease (MASLD)'that is presented here, deals with the …
Liver steatosis linked to type 2 diabetes outcomes
N Bhala - bmj, 2024 - bmj.com
Although non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis are
increasingly recognised globally, 1 these terms were updated in June 2023 by an …
increasingly recognised globally, 1 these terms were updated in June 2023 by an …
Prediction of early recovery of graft function after living donor liver transplantation in children
B Tan, C Yang, J Hu, H Xing, M Zhang - Scientific Reports, 2024 - nature.com
For end-stage liver disease in children, living donor liver transplantation (LDLT) is often the
important standard curative treatment. However, there is a lack of research on early recovery …
important standard curative treatment. However, there is a lack of research on early recovery …
Liver fibrosis assessed via non-invasive tests is associated with incident heart failure in a general population cohort
TJ Hydes, OJ Kennedy, K Glyn-Owen… - Clinical …, 2024 - Elsevier
Background & Aims The aim of this study was to determine whether liver fibrosis is
associated with heart failure in a general population cohort, and if genetic polymorphisms …
associated with heart failure in a general population cohort, and if genetic polymorphisms …
Effect of essential phospholipids on hepatic steatosis in metabolic dysfunction-associated steatotic liver disease associated with type 2 diabetes mellitus and/or …
N Stefan, M Hartleb, B Popovic, R Varona - Trials, 2024 - Springer
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a
predominant chronic liver condition globally and is strongly associated with obesity …
predominant chronic liver condition globally and is strongly associated with obesity …
Effect of pemvidutide, a GLP-1/glucagon dual receptor agonist, on MASLD: A randomized, double-blind, placebo-controlled study
SA Harrison, SK Browne, JJ Suschak, S Tomah… - Journal of …, 2024 - Elsevier
Abstract Background & Aims This was a randomized, double-blind, placebo-controlled study
to assess the effects of pemvidutide, a glucagon-like peptide-1 (GLP-1)/glucagon dual …
to assess the effects of pemvidutide, a glucagon-like peptide-1 (GLP-1)/glucagon dual …
Elevated FIB-4 Is Associated with Higher Rates of Cardiovascular Disease and Extrahepatic Cancer History in Patients with Type 2 Diabetes Mellitus
DS Karagiannakis, K Stefanaki, F Petrea, P Zacharaki… - Biomedicines, 2024 - mdpi.com
Background: Type 2 diabetes mellitus (T2DM) is often complicated by steatotic liver disease,
cardiovascular disease (CVD), and extrahepatic cancer. We investigated whether FIB-4, an …
cardiovascular disease (CVD), and extrahepatic cancer. We investigated whether FIB-4, an …