Integrative genome-wide analyses identify novel loci associated with kidney stones and provide insights into its genetic architecture
X Hao, Z Shao, N Zhang, M Jiang, X Cao, S Li… - Nature …, 2023 - nature.com
Kidney stone disease (KSD) is a complex disorder with high heritability and prevalence. We
performed a large genome-wide association study (GWAS) meta-analysis for KSD to date …
performed a large genome-wide association study (GWAS) meta-analysis for KSD to date …
Magnesium for disease treatment and prevention: emerging mechanisms and opportunities
Q Gao, O Cil - Trends in Pharmacological Sciences, 2024 - cell.com
Abstract Magnesium (Mg 2+) is a commonly used dietary supplement for the prevention and
treatment of diseases. However, the efficacy and mechanisms of action of Mg 2+ in most …
treatment of diseases. However, the efficacy and mechanisms of action of Mg 2+ in most …
Association between oxidative balance score and kidney stone in United States adults: analysis from NHANES 2007-2018
R Ke, Y He, C Chen - Frontiers in Physiology, 2023 - frontiersin.org
Purpose: To investigate the relationship between the Oxidative Balance Score (OBS) and
kidney stone risk using NHANES 2007-2018 data, and to explore potential mechanisms and …
kidney stone risk using NHANES 2007-2018 data, and to explore potential mechanisms and …
Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway
Y Mao, J Yu, J Da, F Yu, Y Zha - PeerJ, 2023 - peerj.com
ABSTRACT Purpose. Acteoside (Act), a phenylethanoid compound that was first isolated
from mullein, has been widely used for the investigation of anti-inflammatory and antifibrotic …
from mullein, has been widely used for the investigation of anti-inflammatory and antifibrotic …
Metabolic evaluation: is there really a future?
O Traxer, M Corrales, A Sierra - Current Opinion in Urology, 2022 - journals.lww.com
It is important for us, urologists, to have in mind the actual stone prevalence worldwide. As
part of our initial evaluation of the patient with urolithiasis, we must not forget to perform the …
part of our initial evaluation of the patient with urolithiasis, we must not forget to perform the …
Relationship between serum selenium level and self-reported history of kidney stone
A Wang, N Wang, D Zhang, J Wen, W Wang - Nutrients, 2023 - mdpi.com
A relationship may exist between selenium and kidney calculi, but there is a lack of research
in this field at present. Our study explored the relationship between the serum selenium level …
in this field at present. Our study explored the relationship between the serum selenium level …
Primary contributors to dietary acid load in patients with urolithiasis
MV Betz, KL Penniston - Journal of Renal Nutrition, 2023 - Elsevier
Objectives In susceptible individuals, high dietary acid load may contribute to the formation
of certain types of kidney stones via lowering urine pH and citrate excretion. The objective of …
of certain types of kidney stones via lowering urine pH and citrate excretion. The objective of …
The magnesium depletion score is associated with increased likelihood of kidney stone disease among female adults
Y Xu, Y Qin, H Lu, L Liu, W Huang, A Huang… - Journal of Trace …, 2024 - Elsevier
Object The association between magnesium depletion score (MDS) and kidney stone
disease (KSD) remains unknown. This study was designed to investigate the association of …
disease (KSD) remains unknown. This study was designed to investigate the association of …
Urinary acidification does not explain the absence of nephrocalcinosis in a mouse model of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis …
A Al-Shebel, G Michel, T Breiderhoff… - International Journal of …, 2024 - mdpi.com
Patients with mutations in Cldn16 suffer from familial hypomagnesaemia with hypercalciuria
and nephrocalcinosis (FHHNC) which can lead to renal insufficiency. Mice lacking claudin …
and nephrocalcinosis (FHHNC) which can lead to renal insufficiency. Mice lacking claudin …
The impacts of metabolic syndrome on the risk of severe urolithiasis
Q Fu, L Xie, C Diao, X Aizezi, X Liu, C Liu - Urolithiasis, 2022 - Springer
Metabolic syndrome (MetS) is significantly correlated with urolithiasis. However, few studies
have evaluated the severity of urolithiasis. This study aimed to investigate the relationship of …
have evaluated the severity of urolithiasis. This study aimed to investigate the relationship of …