Objective Provide recommendations to the cystic fibrosis (CF) community to facilitate timely
referral for lung transplantation for individuals with CF. Methods The CF Foundation …

Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral …

Background Advanced cystic fibrosis lung disease (ACFLD) is common, is associated with
reduced quality of life, and remains the most frequent cause of death in individuals with …

Lung transplantation: candidate selection and timing of tran... : Current Opinion in Organ
Transplantation Lung transplantation: candidate selection and timing of transplant : Current …

Metformin is an activator of the AMPK and Nrf2 pathways which are important in the
pathology of several complex pulmonary diseases with unmet medical needs. Organic …

Background Pulmonary artery (PA) enlargement, defined as pulmonary artery to ascending
aorta diameter ratio (PA: A)> 1 on computed tomography (CT), is a marker of pulmonary …

Inhalable nanostructured microparticles of simvastatin, a Nrf2 activator and RhoA/Rho
kinase (ROCK) inhibitor, were rationally designed for targeted pulmonary delivery as dry …

While remarkable advances in cystic fibrosis (CF) care have led to improvements in survival
and quality of life, many individuals with CF are living with advanced cystic fibrosis lung …

Purpose Cystic fibrosis (CF) is a progressive disease resulting in end-stage lung disease.
Lung transplantation (LTx) is an important consideration in these patients. Studies have …

Introduction: Survival after lung transplantation lags behind outcomes of other solid organ
transplants, and complications from lung transplant are the second most common cause of …