Low folate intake and serum levels are associated with higher body mass index and abdominal fat accumulation: a case control study

MA Mlodzik-Czyzewska, AM Malinowska… - Nutrition Journal, 2020 - Springer
Background The link between folate metabolism and obesity has recently been underlined,
suggesting that folate deficiency may lead to body weight gain and adiposity. We thus …

Causal effects of B vitamins and homocysteine on obesity and musculoskeletal diseases: A Mendelian randomization study

L Fu, Y Wang, YQ Hu - Frontiers in Nutrition, 2022 - frontiersin.org
Objectives Although homocysteine (Hcy) increases the risk of cardiovascular diseases, its
effects on obesity and musculoskeletal diseases remain unclear. We performed a Mendelian …

Central but not general obesity is positively associated with the risk of hyperhomocysteinemia in middle-aged women

Y Wang, Y Jiang, N Wang, M Zhu, X Liu, R Wang… - Nutrients, 2019 - mdpi.com
Objective: Obesity and homocysteine (Hcy) are two important risk factors for cardiovascular
disease (CVD). However, evidence on the association between obesity and Hcy …

Association of obesity with the risk of hyperhomocysteinemia among the Chinese community residents: a prospective cohort study in Shanghai, China

Y Xiang, Q Zhao, N Wang, Y Yu, R Wang, Y Zhang… - Nutrients, 2021 - mdpi.com
A prospective community-based cohort study was conducted to investigate the effects of
obesity on hyperhomocysteinemia (HHcy) in community residents from Shanghai, China …

Association between high BMI and high homocysteine levels in Chinese patients with bipolar disorder

L Mu, F Yu, J Xia, XE Lang, A Haque, HE Wu… - Journal of affective …, 2021 - Elsevier
Background Bipolar disorder (BD) has been associated with an increased prevalence of
weight gain and abnormally elevated plasma homocysteine (Hcy) levels. However, the …

Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress

AI Preninka, K Kuriya, K Yazawa, M Yoshii, Y Yanase… - Plos one, 2022 - journals.plos.org
Abnormally high serum homocysteine levels have been associated with several disorders,
including obesity, cardiovascular diseases or neurological diseases. Leptin is an anti …

First trimester maternal homocysteine and embryonic and fetal growth: the Rotterdam Periconception Cohort

E Rubini, KM Snoek, S Schoenmakers, SP Willemsen… - Nutrients, 2022 - mdpi.com
Homocysteine is a marker for derangements in one-carbon metabolism. Elevated
homocysteine may represent a causal link between poor maternal nutrition and impaired …

Vitamin D3 reduces risk of cardiovascular and liver diseases by lowering homocysteine levels: double-blinded, randomised, placebo-controlled trial

N Al-Bayyari, R Hailat, H Subih, H Alkhalidy… - British Journal of …, 2021 - cambridge.org
The objective of this study was to evaluate the effect of vitamin D3 on total homocysteine
(tHcy) and C-reactive protein (CRP) levels and liver and kidney function tests in overweight …

Methylenetetrahydrofolate Reductase C677T Gene Variant in Relation to Body Mass Index and Folate Concentration in a Polish Population

M Wrzosek, K Ślusarczyk - Biomedicines, 2022 - mdpi.com
Background: Methylenetetrahydrofolate reductase (MTHFR) is an enzyme responsible for
producing an active form of folate. The MTHFR T677T genotype may have adverse health …

The relationship of circulating homocysteine with fibrinogen, blood pressure, and other cardiovascular measures in African adolescents

JP du Plessis, C Nienaber-Rousseau… - The Journal of …, 2021 - Elsevier
Objectives To evaluate the associations between homocysteine (Hcy) and cardiovascular
health in South African adolescents. Study design Circulating Hcy concentrations of 172 …