Introduction: Inhaled antibiotics are probably the safest and most effective therapy for
Pseudomonas aeruginosa chronic lung infection in cystic fibrosis (CF) patients. Areas …

Inhaled antibiotics, such as tobramycin, for the treatment of Pseudomonas aeruginosa
pulmonary infections are associated with the increase in life expectancy seen in cystic …

Drug delivery to the mucus covered mucosae is fraught with difficulties and many different
approaches have been developed to permeate the mucus barrier. Generally by modifying …

The effect of different amino acids (AAs) on the aerosol performance of N spray-dried
powders was studied. Morphology, size distribution, density, dissolution rate were evaluated …

Cystic fibrosis (CF) patients are suffering from multiple often chronic endobronchial infection.
The stiff mucus in these patients represents a compartment, which cannot easily be reached …

There is currently less experience with inhaled tobramycin in non-cystic fibrosis
bronchiectasis than in cystic fibrosis (CF). Intravenous formulation and solution for inhalation …

Pseudomonas aeruginosa is an opportunistic multidrug resistant pathogen causing severe
chronic infections. Our previous studies showed that elevated calcium (Ca 2+) enhances …

Here, nano into micro formulations (NiMs) of tobramycin for the treatment of Pseudomonas
aeruginosa airway infections in cystic fibrosis (CF) are described. NiMs were produced by …

Inhaled antimicrobials have been extremely beneficial in treating respiratory infections,
particularly chronic infections in a lung with cystic fibrosis. The pulmonary delivery of …

Purpose Pulmonary antibiotic delivery is recommended as maintenance therapy for cystic
fibrosis (CF) patients who experience chronic infections. However, abnormally thick and …