OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES

JK Choi, W Xiao, X Chen, S Loghavi… - Modern Pathology, 2024 - Elsevier
This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

The role of FLT3 in haematopoietic malignancies

DL Stirewalt, JP Radich - Nature Reviews Cancer, 2003 - nature.com
Normal haematopoietic cells use complex systems to control proliferation, differentiation and
cell death. The control of proliferation is, in part, accomplished through the ligand-induced …

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute …

JC Byrd, K Mrózek, RK Dodge… - Blood, The Journal …, 2002 - ashpublications.org
We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to
ascertain the prognostic impact of cytogenetic abnormalities on complete remission (CR) …

Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative …

ML Slovak, KJ Kopecky, PA Cassileth… - Blood, The Journal …, 2000 - ashpublications.org
The associations of cytogenetics with complete remission (CR) rates, overall survival (OS),
and outcomes after CR were studied in 609 previously untreated AML patients younger than …

Morphological and immunophenotypic clues to the WHO categories of acute myeloid leukaemia

BJ Bain, MC Béné - Acta haematologica, 2019 - karger.com
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and
molecular genetic investigation. However, while these evaluations are pending, morphology …

Clinical importance of cytogenetics in acute myeloid leukaemia

K Mrózek, K Heinonen, CD Bloomfield - Best Practice & Research Clinical …, 2001 - Elsevier
Acquired chromosome aberrations are present in the marrow of most patients with acute
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …

[PDF][PDF] Myelodysplastic syndromes: recent advances

EP Alessandrino, S Amadori, M Cazzola… - …, 2001 - haematologica.org
1Department of Hematology, University of Pavia School of Medicine, IRCCS Policlinico S.
Matteo, Pavia; 2Dept. of Hematology, University Tor Vergata, Rome; 3Division of …

The immunophenotype of adult acute myeloid leukemia: high frequency of lymphoid antigen expression and comparison of immunophenotype, French-American …

HS Khalidi, LJ Medeiros, KL Chang… - American journal of …, 1998 - academic.oup.com
Immunophenotyping has become common in the diagnosis and classification of acute
leukemias and is particularly important in the proper identification of cases of minimally …

A retrospective study of 69 patients with t (6; 9)(p23; q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid …

ML Slovak, H Gundacker, CD Bloomfield, G Dewald… - Leukemia, 2006 - nature.com
Leukemia (2006) 20, 1295–1297. doi: 10.1038/sj. leu. 2404233; published online 20 April
2006 t (6; 9)(p23; q34) is a rare recurring cytogenetic aberration resulting in the formation of …

11q23 balanced chromosome aberrations in treatment‐related myelodysplastic syndromes and acute leukemia: report from an international workshop

CD Bloomfield, KJ Archer, K Mrózek… - Genes …, 2002 - Wiley Online Library
Among 511 patients with therapy‐related myelodysplastic syndrome or acute leukemia (t‐
MDS/t‐AL) and balanced chromosome aberrations, 162 (32%) had translocations involving …