Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism
NQV Tran, K Miyake - International journal of genomics, 2017 - Wiley Online Library
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …
Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery
KM Kantak - Pharmacology Biochemistry and Behavior, 2022 - Elsevier
There are over twenty rodent models of Attention-Deficit Hyperactivity Disorder (ADHD), with
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …
most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6 …
Human brain organoid-on-a-chip to model prenatal nicotine exposure
Nicotine has been recognized to trigger various neuronal disabilities in the fetal brain and
long-lasting behavioral deficits in offspring. However, further understanding of fetal brain …
long-lasting behavioral deficits in offspring. However, further understanding of fetal brain …
[HTML][HTML] The effects of prenatal cigarette and e-cigarette exposure on infant neurobehaviour: a comparison to a control group
S Froggatt, N Reissland, J Covey - EClinicalMedicine, 2020 - thelancet.com
Background Infant neurobehaviour provides an insight into the development of the central
nervous system during infancy, with behavioural abnormalities highlighting a cause for …
nervous system during infancy, with behavioural abnormalities highlighting a cause for …
Molecular mechanisms for nicotine intoxication
T Alkam, T Nabeshima - Neurochemistry International, 2019 - Elsevier
Nicotine, one of the more than 4700 ingredients in tobacco smoke, is a neurotoxin and once
used as pesticides in agriculture. Although its use in agriculture is prohibited in many …
used as pesticides in agriculture. Although its use in agriculture is prohibited in many …
A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes
J Zhu, F Fan, DM McCarthy, L Zhang… - International Journal of …, 2017 - Elsevier
Prenatal exposure to nicotine via cigarette smoke or other forms of tobacco use is a
significant environmental risk factor for attention deficit hyperactivity disorder (ADHD). The …
significant environmental risk factor for attention deficit hyperactivity disorder (ADHD). The …
[HTML][HTML] New research perspectives on the interplay between genes and environment on executive function development
PM Miguel, MJ Meaney, PP Silveira - Biological Psychiatry, 2023 - Elsevier
Executive functions (EFs) are a set of skills responsible for the cognitive control of emotional
states and behavior as well as for information processing required for learning and memory …
states and behavior as well as for information processing required for learning and memory …
Prenatal nicotine exposure in mice induces sex-dependent anxiety-like behavior, cognitive deficits, hyperactivity, and changes in the expression of glutamate receptor …
In rodents, prenatal nicotine exposure (PNE) has been associated with increased risk for
development of cognitive and emotional disturbances, but the findings are somewhat …
development of cognitive and emotional disturbances, but the findings are somewhat …
Electronic cigarette use during preconception and/or pregnancy: Prevalence, characteristics, and concurrent mental health conditions
LG Rollins, NA Sokol, M McCallum… - Journal of Women's …, 2020 - liebertpub.com
Background: Electronic cigarettes (e-cigarettes) are increasing in popularity in the United
States. Prior prevalence estimates of e-cigarette use in pregnancy range from 1% to 15 …
States. Prior prevalence estimates of e-cigarette use in pregnancy range from 1% to 15 …
Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes
A Sobue, N Ito, T Nagai, W Shan, K Hada, A Nakajima… - Glia, 2018 - Wiley Online Library
In the central nervous system, major histocompatibility complex class I (MHCI) molecules are
mainly expressed in neurons, and neuronal MHCI have roles in synapse elimination and …
mainly expressed in neurons, and neuronal MHCI have roles in synapse elimination and …