Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction

RM Yildirim, E Seli - Human Reproduction, 2024 - academic.oup.com
Mitochondria are commonly recognized as the powerhouses of the cell, primarily
responsible for energy production through oxidative phosphorylation. Alongside this vital …

Investigating developmental characteristics of biopsied blastocysts stratified by mitochondrial copy numbers using time-lapse monitoring

CI Lee, CY Su, HH Chen, CC Huang, EH Cheng… - Reproductive Biology …, 2024 - Springer
Background For in vitro fertilization (IVF), mitochondrial DNA (mtDNA) levels in the
trophectodermal (TE) cells of biopsied blastocysts have been suggested to be associated …

[PDF][PDF] Clinical whole-genome sequencing-based haplarithmisis enables simple, scalable, and universal preimplantation genetic testing

A Janssen, RM Koeck, R Essers… - GENOME AND … - cris.maastrichtuniversity.nl
Preimplantation genetic testing (PGT) is a widely used method to select in vitrofertilised
embryos that do not harbour severe genetic abnormalities, thereby reducing the burden of …