[HTML][HTML] Emerging evidence that the mammalian sperm epigenome serves as a template for embryo development
Increasing evidence suggests parental environmental stressors can influence offspring
health and disease outcomes. In this perspective, the authors provide an update of the …
health and disease outcomes. In this perspective, the authors provide an update of the …
[HTML][HTML] Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
[HTML][HTML] Primate-specific transposable elements shape transcriptional networks during human development
The human genome contains more than 4.5 million inserts derived from transposable
elements (TEs), the result of recurrent waves of invasion and internal propagation …
elements (TEs), the result of recurrent waves of invasion and internal propagation …
A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility
AA Ruggieri, L Livraghi, JJ Lewis, E Evans… - Genome …, 2022 - genome.cshlp.org
Despite insertions and deletions being the most common structural variants (SVs) found
across genomes, not much is known about how much these SVs vary within populations and …
across genomes, not much is known about how much these SVs vary within populations and …
[HTML][HTML] Regulation of human trophoblast gene expression by endogenous retroviruses
JM Frost, SM Amante, H Okae, EM Jones… - Nature structural & …, 2023 - nature.com
Regulation of human trophoblast gene expression by endogenous retroviruses | Nature
Structural & Molecular Biology Skip to main content Thank you for visiting nature.com. You are …
Structural & Molecular Biology Skip to main content Thank you for visiting nature.com. You are …
[HTML][HTML] Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk
S Kojima, S Koyama, M Ka, Y Saito, EH Parrish… - Nature Genetics, 2023 - nature.com
Mobile element variation contributes to population-specific genome diversification, gene
regulation and disease risk | Nature Genetics Skip to main content Thank you for visiting …
regulation and disease risk | Nature Genetics Skip to main content Thank you for visiting …
[HTML][HTML] Hijacking of transcriptional condensates by endogenous retroviruses
V Asimi, A Sampath Kumar, H Niskanen… - Nature Genetics, 2022 - nature.com
Most endogenous retroviruses (ERVs) in mammals are incapable of retrotransposition;
therefore, why ERV derepression is associated with lethality during early development has …
therefore, why ERV derepression is associated with lethality during early development has …
[HTML][HTML] The regulation of totipotency transcription: Perspective from in vitro and in vivo totipotency
H Xu, H Liang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Totipotency represents the highest developmental potency. By definition, totipotent stem
cells are capable of giving rise to all embryonic and extraembryonic cell types. In …
cells are capable of giving rise to all embryonic and extraembryonic cell types. In …
[HTML][HTML] Evolutionarily recent retrotransposons contribute to schizophrenia
Transposable elements (TEs) are mobile genetic elements that constitute half of the human
genome. Recent studies suggest that polymorphic non-reference TEs (nrTEs) may …
genome. Recent studies suggest that polymorphic non-reference TEs (nrTEs) may …
Transposable elements in mammalian chromatin organization
Transposable elements (TEs) are mobile DNA elements that comprise almost 50% of
mammalian genomic sequence. TEs are capable of making additional copies of themselves …
mammalian genomic sequence. TEs are capable of making additional copies of themselves …