Abstract Background Long non-coding RNAs (lncRNAs) constitute a novel class of non-
coding RNAs. LncRNAs regulate gene expression, thus having the possibility to modulate …

The past decade has seen an explosion of interest in long noncoding RNAs (lncRNAs).
However, despite the massive volume of scientific data implicating these transcripts in a …

The limitations of central nervous system (CNS) drug delivery conferred by the blood-brain
barrier (BBB) have been a significant obstacle in the development of large molecule …

Long noncoding RNAs (lncRNA) are emerging as major regulators of cellular phenotypes
and implicated as oncogenes or tumor suppressors. Here, we report a novel tumor …

Epigenetic processes in the brain involve the transfer of information arising from short-lived
cellular signals and changes in neuronal activity into lasting effects on gene expression. Key …

Abstract Background/Aims: The novel long noncoding RNA (lncRNA) tumor suppressor
candidate 7 (TUSC7) has been reported as a potential tumor suppressor, while the …

Approximately 50 million people have epilepsy, making it the most common chronic and
severe neurological disease worldwide, with increased risk of mortality and psychological …

Whole-transcriptome analyses have revealed that a large proportion of the human genome
is transcribed in non-protein-coding transcripts, designated as long non-coding RNAs …

Abstract Growth arrest-specific 5 (GAS5) lncRNA promotes apoptosis, and its expression is
down-regulated in breast cancer. GAS5 lncRNA is a decoy of glucocorticoid/related …

Long non-coding RNA (lncRNA), a member of non-coding RNA family with over 200
nucleotides in length, typically serves as an oncogene or tumor suppressor in tumor …